Results 31 to 40 of about 4,381 (132)

Interior Decorative VOCs Elevate T Cell‐Mediated Obstructive Lung Disease Risks via Osteogenesis‐Driven Lymphoid‐Biased Hematopoiesis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study utilizes a whole‐body inhalation model to reveal that interior decorative VOCs exposure persistently elevates alveolar T cells. This increase is attributed to lymphoid‐biased hematopoiesis in the bone marrow, which is further driven by IL‐6/IL‐17A‐mediated osteogenic differentiation.
Hongyan Yu, Jingxu Zhang, Qingping Liu, Duxing Li, Ruonan Pan, Gan Miao, Yidi Chen, Zhe Kou, Guangbo Qu, Rong Zhang, Xiaoting Jin, Yuxin Zheng   +11 more
wiley   +1 more source

Overcoming EGFR‐Mediated Dendritic Cell Dysfunction to Enhance Anti‐tumor Immunity in EGFR‐Mutant NSCLC by Precisely Targeting CD73 With pH‐responsive Nanocarriers

Advanced Science, Volume 13, Issue 1, 5 January 2026.
EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang, Xudong Geng, Zixu Wang, Shumin Yuan, Shanshan Ding, Ni Liu, Xinchun Ma, Xuan Sun, Huimin Wang, Ying Sun, Xun Qu, Guangwen Ren, Yong Qiang Li, Xiuwen Wang, Yanguo Liu   +14 more
wiley   +1 more source

Studies of the Phosphorylation of the Herpes Simplex Virus Type 1 Encoded Deoxyribonuclease and Ribonucleotide Reductase [PDF]

, 1991
The herpes virus, herpes simplex type 1 (HSV-1) contains around 70 genes, most of which are expressed during lytic infection of BHK cells in culture. Two of the enzymes encoded by herpes simplex type 1 were studied using enzymatic, electrophoretic and ...
Harvie, Douglas George
core  

Alternative Approaches to Combat Medicinally Important Biofilm-Forming Pathogens [PDF]

, 2018
Bacteria have developed the capability to produce structured communities (or cluster of cells) via adherence to surface to form biofilms that facilitate or prolong their survival under extreme environmental condition.
Palanisamy, Navindra Kumari, Saleemi, Mansab Ali, Wong, Eng Hwa   +2 more
core   +1 more source

Self‐Assembled Nanocomplexes of Oligomerized Catechins and Deoxyribonuclease‐I for Synergistically Enhancing Diabetic Wound Healing

Aggregate, Volume 7, Issue 1, January 2026.
This study develops a self‐assembled O/DNase‐I nanocomplex that eliminates neutrophil extracellular traps (NETs) and blocks their formation, accelerates diabetic ulcers (DUs) healing in mice through the synergetic effect of DNase‐I and oligomerized epigallocatechin gallate (OEGCG).
Yue Li, Yuye Yang, Huiying Zhang, Rongshuang Xin, Xinyi Pang, Tianxin Li, Wei Liu, Xin Zhou, Zinuo Zhang, Sailong Wang, Xinwei Miao, Jie Dong, Yan Zheng, Zhigui Su, Jun Chen, Mei Dong   +15 more
wiley   +1 more source

Identification of a new family of putative PD-(D/E)XK nucleases with unusual phylogenomic distribution and a new type of the active site [PDF]

, 2005
BACKGROUND: Prediction of structure and function for uncharacterized protein families by identification of evolutionary links to characterized families and known structures is one of the cornerstones of genomics.
Bujnicki, Janusz M, Feder, Marcin
core   +2 more sources

Targeting neutrophil‐driven immunosuppression: A strategy to overcome immune checkpoint inhibitor resistance

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
TANs drive ICI resistance via antitumour immune remodelling, angiogenesis promotion, and elevation of tumour mutation burden Neutrophil biomarkers (e.g., NLR, TAN abundance) show strong predictive value for ICI response and prognosis. Targeting TAN recruitment, polarization, function and NETosis represents a promising strategy to overcome ICI ...
Ying Ning, Ke Lei, Xinyan Gao, Yan Kong, Yuping Shan, Tian Tian, Zhumei Cui, He Ren   +7 more
wiley   +1 more source

Investigating the mechanism of aluminum resistance conferred by aluminum resistance protein 1

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Aluminum does not play any role in essential biological processes, but in acidic conditions it becomes biologically reactive and highly toxic even at low concentrations. Eukaryotes have developed numerous strategies for detoxification, one of which relies on membrane proteins.
Pavlo Stehantsev, Artem Stetsenko, Pavla Herynková, Andrei Zupnik, Carsten Takens, Olga Zimmermannova, Hana Sychrova, Albert Guskov   +7 more
wiley   +1 more source

Synergistic Effects in Condensed DNA Framework‐Mediated Synthesis of Amorphous Nanoalloys for Enhanced Electrocatalytic Oxygen Evolution

Small Structures, Volume 7, Issue 1, January 2026.
The condensed DNA framework generates a self‐confined space that facilitates the constrained synthesis of FeCoNi amorphous nanoalloys (FeCoNi ANAs), while simultaneously acting as a dispersant and adhesive, as well as synergistically modulating the coupling of the lattice oxygen mechanism (LOM) and the adsorbate evolution mechanism (AEM), thereby ...
Zhuang Cai, Rui Gao, Jianbang Wang, Huajie Liu   +3 more
wiley   +1 more source

The Effect of Dimethylsulfoxide on the Infectivity of the T1-Coliphage [PDF]

, 1971
A thesis presented to the faculty of the School of Sciences and Mathematics at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science in Biology by Gregory Kyle Reeder on July 22 ...
Reeder, Grergory Kyle
core   +1 more source