Results 31 to 40 of about 16,138 (134)
Food Biomacromolecules, EarlyView.Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo +3 more
wiley +1 more source
MXenes‐based flexible electronics for wound monitoring and treatment
Interdisciplinary Medicine, EarlyView.This article provides a comprehensive overview of recent advancements in MXenes‐based flexible electronic devices for wound monitoring. It discusses the monitoring mechanisms and values for various wound pathological parameters as well as their applications in treating bacterial infections and chronic wounds.
Ye Yang +6 more
wiley +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Molecular imprinting is a very powerful tool in life science. The research areas benefiting from a wide range of capabilities of molecularly imprinted polymeric nanoparticles (nanoMIPs) include sample preparation, extraction, sensing/detection, diagnostics, and drug delivery.
Milada Vodova +2 more
wiley +1 more source
The FEBS Journal, EarlyView.Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés +19 more
wiley +1 more source
Journal of Food Science, Volume 90, Issue 9, September 2025.ABSTRACT The fermented botanical product (FBP) is a complex, primarily plant‐based fermented food that has been popular among consumers for many years. Although FBP may modulate gastrointestinal function, the responsible factors and precise mechanisms remain unclear and speculative.
Kotomi Chikama +8 more
wiley +1 more source
Brain Pathology, Volume 35, Issue 5, September 2025.HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie +9 more
wiley +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Advanced Science, Volume 12, Issue 29, August 7, 2025.Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu +5 more
wiley +1 more source
Advanced Science, Volume 12, Issue 30, August 14, 2025.Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu +13 more
wiley +1 more source
Two Key Ferredoxins for Nitrogen Fixation Have Different Specificities and Biophysical Properties
Chemistry – A European Journal, Volume 31, Issue 37, July 2, 2025.Two ferredoxins, FdC and FdN, are collectively essential for the process of nitrogen fixation by the iron nitrogenase in R. capsulatus. We explore the biophysical factors, through spectroscopic and structural characterizations, which determine ferredoxin functionality and pathway specificity. The structure of FdC (PDB: 9I2A) and model of FdN (AF‐D5ARY6)
Holly Addison +5 more
wiley +1 more source
Classification and evolution of type II CRISPR-Cas systems
Nucleic Acids Research, 2014 The CRISPR-Cas systems of archaeal and bacterial adaptive immunity are classified into three types that differ by the repertoires of CRISPR-associated (cas) genes, the organization of cas operons and the structure of repeats in the CRISPR arrays.
Krzysztof Chylinski +3 more
semanticscholar +1 more source