Results 121 to 130 of about 87,543 (295)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Modeling the Dependency Structure of Stock Index Returns using a Copula Function Approach [PDF]

In the present study we assess the dependency structure between stock indexes by econometrically estimating the empirical copula function and the parameters of various parametric copula functions.
Necula, Ciprian
core  

No 'return to the state': dependency and developmentalism against neo-liberalism

, 2008
In the emerging 'post-Washington Consensus' era, neo-liberalism is searching for alternatives that once again emphasise the state. Yet neither Latin American dependencia nor East Asian developmentalism - two development models actually practised 'on the ...
Kelly, Robert E
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Re-inscribing dependency : the political economy of Mauritius JinFei Economic and Trade Cooperation Zone Co. Ltd.

, 2015
This thesis investigates the capacity of the newly introduced Chinese Special Economic Zones in Africa (CSEZAs) to deliver ‘cooperation’ and ‘mutual development’ to China and Africa.
Cowaloosur, Honita
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The transnational formation of dependency theory [PDF]

The set of analyses and reflections known as the dependency theory is today considered one of the main Latin American contributions to the field of Western social sciences, having become, since 1980,  a historical category par excellence for ...
Giorgini, Flores, Flores Giorgini
core   +1 more source

Unpacking environmental racism through dependency theory in the case of second-hand goods export to West Africa

Discover Environment
The second-hand goods export market is complex and inextricably intertwined with environmental racism and dependency theories. Studies have shown that the adverse impacts of second-hand goods exports outweigh their benefits.
Prince Nii Koi Kotei, Kwadwo Adusei-Asante, Shajimon Peter, Portia Nana Ama Brempong   +3 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A formação de alianças estratégicas: uma análise teórica a partir da teoria da dependência de recursos e da teoria dos custos de transação

Cadernos EBAPE.BR
A formação de alianças estratégicas é uma tendência cada vez mais evidente no atual ambiente organizacional, sendo uma das principais estratégias utilizadas pelas organizações para manterem-se competitivas.
Leonardo Querido Cárdenas, Fernando Dias Lopes   +1 more
doaj   +1 more source