Results 1 to 10 of about 6,507 (124)

Novel parvoviruses from wild and domestic animals in Brazil provide new insights into parvovirus distribution and diversity [PDF]

Viruses, 2018
Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified.
de Araujo, Jansen, de Oliveira Torres Carrasco, Adriano, de Souza, William Marciel, Dennis, Tristan, Durigon, Edison Luiz, Figueiredo, Luiz Tadeu Moraes, Fumagalli, Marcílio Jorge, Gifford, Robert James, Gonçalves Motta Maia, Felipe, Modha, Sejal, Nunes, Márcio Roberto Teixeira, Olszanski Acrani, Gustavo, Ometto, Tatiana, Queiroz, Luzia Helena, Romeiro, Marilia Farignoli, Sabino-Santos Jr., Gilberto, Vieira, Luiz Carlos   +16 more
core   +5 more sources

Non‐A to E hepatitis in children: Detecting a novel viral epidemic during the COVID‐19 pandemic

Microbial Biotechnology, 2023
During the COVID‐19 pandemic, two further novel viral epidemics were described in 2022, monkeypox virus infections in men having sex with men and non‐A to E hepatitis in children.
Harald Brüssow
doaj   +2 more sources

Development of a fluorescent quantitative real-time polymerase chain reaction assay for the detection of Goose parvovirus in vivo [PDF]

Virology Journal, 2009
Background Goose parvovirus (GPV) is a Dependovirus associated with latent infection and mortality in geese. Currently, it severely affects geese production worldwide.
Chen, Xiao-Yue, Cheng, An-Chun, Guo, Yu-Fei, Li, Chuan-Feng, Li, Min, Pan, Kang-Cheng, Wang, Ming-Shu, Yang, Jin-Long, Zhu, De-Kang   +8 more
core   +5 more sources

A simple and rapid method for detection of Goose Parvovirus in the field by loop-mediated isothermal amplification [PDF]

Virology Journal, 2010
Background Goose parvovirus (GPV) is a Dependovirus associated with latent infection and mortality in geese. Currently, in a worldwide scale, GPV severely affects geese production.
Cheng AnChun, Fu LiZhi, JinLong, Yang, Wang MingShu, Xu ZhiYong, Yang Liu, Yang Rui, Yang SongQuan, Yang YangJinLong, Zhang SuHui   +9 more
core   +4 more sources

A sensitive and reproducible cell-based assay via secNanoLuc to detect neutralizing antibody against adeno-associated virus vector capsid

Molecular Therapy: Methods & Clinical Development, 2021
Most gene therapy clinical trials that systemically administered adeno-associated virus (AAV) vector enrolled only patients without anti-AAV-neutralizing antibodies.
Nemekhbayar Baatartsogt, Yuji Kashiwakura, Morisada Hayakawa, Nobuhiko Kamoshita, Takafumi Hiramoto, Hiroaki Mizukami, Tsukasa Ohmori   +6 more
doaj   +1 more source

The seroprevalence of neutralizing antibodies against the adeno-associated virus capsids in Japanese hemophiliacs

Molecular Therapy: Methods & Clinical Development, 2022
Adeno-associated virus (AAV) vectors are promising modalities of gene therapy to address unmet medical needs. However, anti-AAV neutralizing antibodies (NAbs) hamper the vector-mediated therapeutic effect.
Yuji Kashiwakura, Nemekhbayar Baatartsogt, Shoji Yamazaki, Azusa Nagao, Kagehiro Amano, Nobuaki Suzuki, Tadashi Matsushita, Akihiro Sawada, Satoshi Higasa, Naoya Yamasaki, Teruhisa Fujii, Taemi Ogura, Hideyuki Takedani, Masashi Taki, Takeshi Matsumoto, Jun Yamanouchi, Michio Sakai, Masako Nishikawa, Yutaka Yatomi, Koji Yada, Keiji Nogami, Ryota Watano, Takafumi Hiramoto, Morisada Hayakawa, Nobuhiko Kamoshita, Akihiro Kume, Hiroaki Mizukami, Shizukiyo Ishikawa, Yoichi Sakata, Tsukasa Ohmori   +29 more
doaj   +1 more source

Astrovirus Outbreak in an Animal Shelter Associated With Feline Vomiting

Frontiers in Veterinary Science, 2021
An outbreak of cat vomiting was observed in an animal shelter. Testing for known enteric feline pathogens did not identify a causative agent. Viral metagenomics on four mini pools of feces from cases and controls housed in the same area revealed the ...
Yanpeng Li, Yanpeng Li, Emilia Gordon, Amanda Idle, Alvin Hui, Roxanne Chan, M. Alexis Seguin, Eric Delwart, Eric Delwart   +8 more
doaj   +1 more source

Gene therapy in neuromuscular disorders

Arquivos de Neuro-Psiquiatria, 2022
Monogenic neuromuscular disorders are potentially treatable through gene therapy. Using viral vectors, a therapeutic transgene aims to restore normal levels of a protein not produced by the defective gene, or to silence a gene whose expression leads to ...
Rodrigo Holanda Mendonça, Edmar Zanoteli   +1 more
doaj   +1 more source

Functional roles of the membrane-associated AAV protein MAAP

Scientific Reports, 2021
With a limited coding capacity of 4.7 kb, adeno-associated virus (AAV) genome has evolved over-lapping genes to maximise the usage of its genome. An example is the recently found ORF in the cap gene, encoding membrane-associated accessory protein (MAAP),
Lionel Galibert, Amira Hyvönen, Reetta A. E. Eriksson, Salla Mattola, Vesa Aho, Sami Salminen, Justin D. Albers, Sanna K. Peltola, Saija Weman, Tiina Nieminen, Seppo Ylä-Herttuala, Hanna P. Lesch, Maija Vihinen-Ranta, Kari J. Airenne   +13 more
doaj   +1 more source

Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. [PDF]

PLoS ONE, 2017
As their names imply, parvoviruses of the genus Dependovirus rely for their efficient replication on the concurrent presence of a helpervirus, such as herpesvirus, adenovirus, or papilloma virus.
Michael Seyffert, Daniel L Glauser, Elisabeth M Schraner, Anna-Paula de Oliveira, Jorge Mansilla-Soto, Bernd Vogt, Hildegard Büning, R Michael Linden, Mathias Ackermann, Cornel Fraefel   +9 more
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