Results 11 to 20 of about 6,602 (127)

Liver virome of a Little Corella (Cacatua sanguinea) reveals coinfection with a novel parvovirus and two beak and feather disease viruses [PDF]

Australian Veterinary Journal, Volume 101, Issue 9, Page 366-372, September 2023., 2023
Emerging diseases are acknowledged as a growing threat to wildlife, with the continued identification of pathogenic and potentially pathogenic viruses in avian species resulting from ongoing advances in molecular diagnostic techniques. Parvoviruses under
Sarker, S., Sutherland, M.
core   +2 more sources

Detection and Genetic Analysis of Porcine Bocavirus [PDF]

The Scientific World Journal, Volume 2014, Issue 1, 2014., 2014
Porcine Bocavirus (PBoV) has been reported to be associated with postweaning multisystemic wasting syndrome and pneumonia in pigs. In this study, a survey was conducted to evaluate the prevalence of PBoV in slaughter pigs, sick pigs, asymptomatic pigs ...
Dong Sun, Jinhai Huang, Lili Guo, Mengmeng Liu, Yi Li, Yihe Xia   +5 more
core   +3 more sources

MiR133b‐mediated inhibition of EGFR‐PTK pathway promotes rAAV2 transduction by facilitating intracellular trafficking and augmenting second‐strand synthesis

Journal of Cellular and Molecular Medicine, Volume 27, Issue 18, Page 2714-2729, September 2023., 2023
Abstract Recombinant adeno‐associated virus (rAAV) is an extremely attractive vector in the in vivo delivery of gene therapy as it is safe and its genome is simple. However, challenges including low permissiveness to specific cells and restricted tissue specificity have hindered its clinical application.
Xiaoping Huang, Xiao Wang, Ling Li, Qizhao Wang, Wentao Xu, Wenlin Wu, Xiaolan Xie, Yong Diao   +7 more
wiley   +1 more source

Molecular mechanisms of amyotrophic lateral sclerosis as broad therapeutic targets for gene therapy applications utilizing adeno‐associated viral vectors

Medicinal Research Reviews, Volume 43, Issue 4, Page 829-854, July 2023., 2023
Abstract Despite the devastating clinical outcome of the neurodegenerative disease, amyotrophic lateral sclerosis (ALS), its etiology remains mysterious. Approximately 90% of ALS is characterized as sporadic, signifying that the patient has no family history of the disease.
Jessica Merjane, Roger Chung, Rickie Patani, Leszek Lisowski   +3 more
wiley   +1 more source

Coinfection of a Bearded Dragon,Pogona vitticeps, with Adenovirus- and Dependovirus-like Viruses [PDF]

Veterinary Pathology, 1996
Four neonate bearded dragons, Pogona vitticeps, from two collections became ill and died. Multiple tissues were collected and processed for light microscopy. In hematoxylin and eosin-stained sections of liver of one lizard, numerous basophilic intranuclear inclusions were observed.
E R, Jacobson, W, Kopit, F A, Kennedy, R S, Funk   +3 more
openaire   +2 more sources

The Analysis of Oral and Fecal Virome Detects Multiple Novel Emerging Viruses in Snakes

Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
Wild animals are considered reservoirs for emerging and reemerging viruses, such as the novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Previous studies have reported that bats and ticks harbored variable important pathogenic viruses, some of which could cause potential diseases in humans and livestock, while viruses carried by ...
Aijing Liu, Zhige Tian, Chuanming Yin, Jie Zou, Shan Wu, Yi Luo, Xin Chen, Yi Dai, Siyi Yang, Yanxi Li, Tongyu Li, Peng Guo, Xiaoliang Hu, Chunfu Zheng   +13 more
wiley   +1 more source

Seroprevalence to adeno‐associated virus type 6 in people with hemophilia B from a UK adult cohort

Research and Practice in Thrombosis and Haemostasis, Volume 6, Issue 4, May 2022., 2022
Abstract Background Gene therapy shows promise as a potential “cure” for hemophilia A and B. Adeno‐associated virus (AAV) vectors are the leading platform to deliver modified genetic code of factor VIII or IX to the liver effecting endogenous production. Patient exposure to wild‐type AAV leads to the formation of neutralizing factors, which can prevent
Sara Boyce, Izabela James, Savita Rangarajan, Nicola Curry, Catherine Bagot, Steven Austin, Mike Laffan, Sarah Mangles, Kandiah Chandrakumaran, Carina Mundy   +9 more
wiley   +1 more source

The Expression Strategy of Goose Parvovirus Exhibits Features of both the Dependovirus and Parvovirus Genera [PDF]

Journal of Virology, 2005
ABSTRACT The RNA transcription profile of the goose parvovirus (GPV) was determined, and it is a surprising hybrid of features of the Parvovirus and Dependovirus genera of the Parvovirinae subfamily of the Parvoviridae . Similar to the
Jianming, Qiu, Fang, Cheng, Yuko, Yoto, Zoltán, Zádori, David, Pintel   +4 more
openaire   +2 more sources

Advancements in molecular design and bioprocessing of recombinant adeno‐associated virus gene delivery vectors using the insect‐cell baculovirus expression platform

Biotechnology Journal, Volume 16, Issue 4, April 2021., 2021
This review focus on the advancements of the molecular design of baculovirus vectors for high yield production of adeno‐associated virus (AAV) vectors for gene delivery describing the different generation of expression vectors with associated advantages and critical limitations.
Pranav R.H. Joshi, Alina Venereo‐Sanchez, Parminder S. Chahal, Amine A. Kamen   +3 more
wiley   +1 more source

An Outbreak of Adenoviral Infection in Inland Bearded Dragons (Pogona Vitticeps) Coinfected with Dependovirus and Coccidial Protozoa (IsosporaSp.) [PDF]

Journal of Veterinary Diagnostic Investigation, 2002
Thirty of 200 (15%) hatchling inland bearded dragons were found dead after a short period (48 hours) of weakness and lethargy. The most common clinical signs were head tilt and circling. Six bearded dragons with neurological signs were euthanized, and postmortem examination revealed no gross abnormalities.
Dae Young, Kim, Mark A, Mitchell, Rudy W, Bauer, Rob, Poston, Doo-Youn, Cho   +4 more
openaire   +2 more sources