Role of the vector genome and underlying factor IX mutation in immune responses to AAV gene therapy for hemophilia B [PDF]
, 2014 BACKGROUND: Self-complementary adeno-associated virus (scAAV) vectors have become a desirable vector for therapeutic gene transfer due to their ability to produce greater levels of transgene than single-stranded AAV (ssAAV).
Ashley T Martino +4 more
core +1 more source
Detection of a novel porcine parvovirus, PPV4, in chinese swine herds [PDF]
, 2010 To determine whether the novel porcine parvovirus type 4 (PPV4) recently reported in America is prevalent in China, a set of specific primers was designed and used for molecular survey of PPV4 among the clinical samples collected from various provinces ...
Cheung, Andrew K +5 more
core +3 more sources
, 2008 Parvovírus são pequenos vírus, cuja designação deriva do latim parvus. Possui duas subfamílias: Parvovirinae e Densovirinae. A subfamília Parvivirinae possui três géneros: Parvovirus, Eritrovirus e Dependovirus.
Rodrigues, Francisco
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Princípios de terapia génica [PDF]
, 2016 Podríamos definir la terapia génica como la introducción de un gen foráneo en el ser humano con fines terapéuticos. La terapia génica comenzó a ser utilizada en el ser humano a principios de los años 90 y en los últimos años ha empezado a dar sus frutos.
Reverter Velasco, Naiara
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Does human bocavirus infection depend on helper viruses? A challenging case report [PDF]
, 2011 A case of severe diarrhoea associated with synergistic human bocavirus type 1 (HBoV) and human herpes virus type 6 (HHV6) is reported. The case supports the hypotheses that HBoV infection under clinical conditions may depend on helper viruses, or that ...
Brockmann, Michael +10 more
core +2 more sources
Класифікація вірусів людини і тварин [PDF]
, 2012 У навчально-методичних рекомендаціях викладено основи загальної вірусології щодо морфології та хімічного складу вірусів, механізму їх репродукції. Розглянуто сучасну класифікацію вірусів і таксономічну характеристику родин вірусів людини і тварин, де ...
Holub, Olena S. +7 more
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Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects [PDF]
, 2017 Over the last decade, pioneering liver-directed gene therapy trials for haemophilia B have achieved sustained clinical improvement after a single systemic injection of adeno-associated virus (AAV) derived vectors encoding the human factor IX cDNA.
A Angelis +213 more
core +1 more source
Meta-transcriptomic discovery of a divergent circovirus and a chaphamaparvovirus in captive reptiles with proliferative respiratory syndrome [PDF]
, 2020 Viral pathogens are being increasingly described in association with mass morbidity and mortality events in reptiles. However, our knowledge of reptile viruses remains limited. Herein, we describe the meta-transcriptomic investigation of a mass morbidity
Chang, W-S +6 more
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Quantitative analysis of waterfowl parvoviruses in geese and Muscovy ducks by real-time polymerase chain reaction: correlation between age, clinical symptoms and DNA copy number of waterfowl parvoviruses [PDF]
, 2012 Background Waterfowl parvoviruses cause serious loss in geese and ducks production. Goose parvovirus (GPV) is infectious for geese and ducks while Muscovy duck parvovirus (MDPV) infects Muscovy ducks only.
Kozdruń, Wojciech +2 more
core +3 more sources
Класифікація вірусів людини і тварин [PDF]
, 2015 У навчально-методичних рекомендаціях викладено основи загальної вірусології щодо морфології та хімічного складу вірусів, механізму їх репродукції. Розглянуто сучасну класифікацію вірусів і таксономічну характеристику родин вірусів людини і тварин, де ...
Holub, Serhii M. +7 more
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