Results 121 to 130 of about 197,985 (303)

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

The depolarization factors for ellipsoids and some of their properties [PDF]

, 2019
The terminology depolarization factors was firstly highlighted in the study of problems involving magnetic, where, it was initially used to describe magnetic properties of material.
Ts. Dr. Herman Wahid
core   +2 more sources

Mitigating pseudo-depolarization in constant-step rotating Mueller matrix polarimetry: An optimized self-registration method

Journal of Innovative Optical Health Sciences
As an emerging powerful tool to provide structural information of tissue specimens label-freely, Mueller matrix (MM) polarimetry has garnered extensive attention in biomedical studies and pathological diagnosis.
Kaisha Deng, Nan Zeng, Liangyu Deng, Qiaoqi Tang, Chunyan Chen, Hongtao Li, Zhiyan Liu, Hui Ma, Chao He, Honghui He   +9 more
doaj   +1 more source

Tachycardia of Atrial Myocytes Induces Collagen Expression in Atrial Fibroblasts through Transforming Growth Factor Beta1

, 2012
AIMS: We investigated the molecular mechanism of rapid- depolarization- induced atrial fibrosis. METHODS AND RESULTS: We used a direct atrial myocyte-fibroblast contact co- culture and a fibroblast-specific transforming growth factor 1 (TGF- 1 ...
蔡佳醍;曾春典;黃瑞仁;吳卓鍇;游治節;王怡智;陳文彬;賴凌平;江福田;林俊立, TSAI, CHIA-TI;TSENG, CHUEN-DEN;HWANG, JUEY-JEN;WU, CHO-KAI;YU, CHIH-CHIEH;WANG, YI-CHIH;CHEN, WEN-PIN;LAI, LING-PING;CHIANG, FU-TIEN;LIN, JIUNN-LEE   +1 more
core  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Collisional Depolarization of Mercury Resonance Radiation

, 1973
The depolarization of mercury resonance radiation (2537 Å), induced in collisions of Hg(63p1) atoms with various buffer gases, has been investigated using the method of delayed coincidences.
K. Hammond, R. A. Phaneuf, L. Krause, J. Pitre   +3 more
core   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Depolarization-associated CircRNA regulate neural gene expression and in some cases may function as templates for translation

Circular RNAs (circRNAs) are a relatively new class of RNA transcript with high abundance in the mammalian brain. Here, we show that circRNAs expression in dierentiated neuroblastoma cells were significantly altered after depolarization with 107 ...
Chantel Fitzsimmons (21138701), Murray Cairns (21136250), Dylan Kiltschewskij (21140069), Ebrahim Mahmoudi (21280277)   +3 more
core  

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source