Results 111 to 120 of about 184,273 (311)

Development of Conductive Mortar for Efficient Sacrificial Anode Cathodic Protection of Reinforced Concrete Structures—Part 2: Four-Year Performance Evaluation in Bridges

open access: yesApplied Sciences
This study explores the efficacy of a sacrificial anode cathodic protection (SACP) system with an activated carbon-based conductive mortar in bridge structures.
Ji-Myung Ha, Jin-A Jeong, Chungkuk Jin
doaj   +1 more source

Tachycardia of Atrial Myocytes Induces Collagen Expression in Atrial Fibroblasts through Transforming Growth Factor Beta1

open access: yes, 2012
AIMS: We investigated the molecular mechanism of rapid- depolarization- induced atrial fibrosis. METHODS AND RESULTS: We used a direct atrial myocyte-fibroblast contact co- culture and a fibroblast-specific transforming growth factor 1 (TGF- 1 ...
蔡佳醍;曾春典;黃瑞仁;吳卓鍇;游治節;王怡智;陳文彬;賴凌平;江福田;林俊立   +1 more
core  

Collisional Depolarization of Mercury Resonance Radiation

open access: yes, 1973
The depolarization of mercury resonance radiation (2537 Å), induced in collisions of Hg(63p1) atoms with various buffer gases, has been investigated using the method of delayed coincidences.
K. Hammond   +3 more
core   +1 more source

The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons [PDF]

open access: yes, 1994
1. Electrotonic responses to 150 ms current pulses were recorded from isolated rat dorsal roots incubated for at least 3 h with either normal (5 mM) or high (25 mM) D-glucose solutions, and with either normal (25 mM) or low (5 mM) bicarbonate ...
U Schneider   +5 more
core   +1 more source

Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics

open access: yesAdvanced Science, EarlyView.
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet   +8 more
wiley   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

open access: yesAdvanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei   +15 more
wiley   +1 more source

β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase

open access: yes, 2004
β-Amyloid (βA) peptide is strongly implicated in the neurodegeneration underlying Alzheimer's disease, but the mechanisms of neurotoxicity remain controversial. This study establishes a central role for oxidative stress by the activation of NADPH oxidase
Abramov, A.Y.   +2 more
core  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Three-channel single-wavelength lidar depolarization calibration

open access: yes, 2017
. Linear depolarization measurement capabilities were added to the CANDAC Rayleigh-Mie-Raman lidar (CRL) at Eureka, Nunavut, in the Canadian High Arctic in 2010.
Graeme Nott   +5 more
core   +1 more source

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