Results 61 to 70 of about 2,320,726 (240)

Weak Hydrogen Bond with Iodide Modulating Crystallization of Methylammonium Lead Iodide for High-Performance Perovskite Solar Cells

Micromachines
The weak hydrogen bond with methylammonium iodide (MAI) dominates the formation of methylammonium lead iodide (MAPbI3) during its nucleation and growth process.
Ning Kang, Lu Li, Zhe Wan, Liping Yang, Zhen Liang, Li Chen, Peng Li, Yongrong Sun, Zuyong Wang, Chenglong Wang   +9 more
doaj   +1 more source

Characteristics and controlling factors of beach-controlled karst reservoirs in Cambrian Longwangmiao Formation, Moxi-Gaoshiti area, Sichuan Basin, NW China

Petroleum Exploration and Development, 2014
Based on data from boreholes, cores and lab analysis, the characteristics, genesis and controlling factors of different types of reservoirs in Cambrian Longwangmiao Formation, Moxi-Gaoshiti area, Sichuan Basin, are examined, and the distribution of ...
Mindong JIN, Wei ZENG, Xiucheng TAN, Ling LI, Zongyin LI, Bing LUO, Jinglei ZHANG, Jiwei LIU   +7 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Effects of Interactions between Feeding Patterns and the Gut Microbiota on Pig Reproductive Performance

Animals
The feeding mode is an important factor affecting the reproductive performance of pigs. The composition and expression of the intestinal microbiota are closely related to the physiological and biochemical indicators of animals.
Mingyu Wang, Jiaqi Yue, Guangquan Lv, Yaxin Wang, Ao Guo, Zhe Liu, Taiyong Yu, Gongshe Yang   +7 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Whole-genome resequencing reveals positive selection and introgression signatures and genetic loci associated with early puberty traits in Chinese indigenous pigs

Genetics Selection Evolution
Background The genetic basis of the phenotypic diversity of pigs is regulated by variants across the genome, especially the trait of early puberty, which is a crucial trait for enhancing the reproductive ability of pigs and the economy of the pig ...
Minghao Cao, Tiantian Yuan, Dong Li, Yulong Wang, Lin Zhang, Jingchun Sun, Guangquan Lv, Rongrong Ding, Taiyong Yu   +8 more
doaj   +1 more source

Modeling the Transport and Retention of Nanoparticles in a Single Partially Saturated Pore in Soil

Water Resources Research, 2023
Pore‐network models are powerful tools for studying particle transport in complex porous media, and investigating the role of interfaces in their fate.
J. Jayaraj, N. Seetha, S. Majid Hassanizadeh   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The hybridization analysis of pedigree: whole-genome re-sequencing reveals genomics characterization and genetic basis of growth trait of Qinchuan black pigs

BMC Genomics
Background Understanding the genetic basis of hybridization trait between Chinese indigenous pig and their commercial relatives may contribute to germplasm innovation. The Qinchuan black (QCB) pig is a new composite breed under development generated from
Minghao Cao, Tiantian Yuan, Dong Li, Xiang Li, Yanyan Huang, Jingchun Sun, Yulong Wang, Taiyong Yu   +7 more
doaj   +1 more source