Results 101 to 110 of about 81,856 (291)

Boron‐Doped Nano‐Crystalline Coated Carbon Fibers for Phasic Dopamine Sensing

Advanced Healthcare Materials, EarlyView.
This uniform coating presents a mix of graphitic and diamond‐like carbon to create a mechanically and electrically robust alternative for the electrochemical detection of dopamine. The electrodes in this work possess the equivalent sensitivity to the state‐of‐the‐art FSCV dopamine detecting electrodes, whilst demonstrating an ability to withstand ...
Simon J. Higham, Juan M. Rojas Cabrera, Youngjong Kwak, Lydia Hong, Andre Chambers, Athavan Nadarajah, Sorel E. De Leon, Young Jun Jung, Negin Jalilinejad, Charles Blaha, Dong Pyo Jang, Yoonbae Oh, Kendall Lee, Alastair Stacey, Shaun L. Cloherty, Michael R. Ibbotson, David J. Garrett, Steven Prawer, Hojin Shin, Wei Tong   +19 more
wiley   +1 more source

The unified protocol for transdiagnostic treatment of emotional disorders compared with diagnosis-specific protocols for anxiety disorders a randomized clinical trial [PDF]

, 2017
IMPORTANCE: Transdiagnostic interventions have been developed to address barriers to the dissemination of evidence-based psychological treatments, but only a few preliminary studies have compared these approaches with existing evidence-based ...
Ametaj, Amantia, Barlow, David H., Bentley, Kate H., Boettcher, Hannah T., Boswell, James F., Bullis, Jacqueline R., Carl, Jenna R., Cassiello-Robbins, Clair, Conklin, Laren R., Farchione, Todd J., Gallagher, Matthew W., Murray-Latin, Heather, Sauer-Zavala, Shannon, Thompson-Hollands, Johanna   +13 more
core   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Fluoxetine: a case history of its discovery and preclinical development [PDF]

, 2014
Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N, Bergstrom RF, Bravo L, Bremner JD, Burrows GD, Chouinard G, Datla KP, Esther Berrocoso, Juan Antonio Mico, Kreiss DS, Laura Perez-Caballero, Lemberger L, Li Q, Lidia Bravo, Maj J, Nibuya M, Owens MJ, Rutter JJ, Sonia Torres-Sanchez, Stevens JC, Wong DT   +20 more
core   +2 more sources

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

Advanced Materials, EarlyView.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas, Bilal Kizilaslan, Aastha Shah, Jason F. Hou, Yoonsoo Shin, Alejandra Hernandez Moyers, Claudia Lozano, Canan Dagdeviren   +7 more
wiley   +1 more source

Behavioral Activation for Treatment-resistant Depression: Theoretical Model and Intervention Protocol (BA-TRD)

Clínica y Salud. Investigación Empírica en Psicología
Background: Treatment-resistant depression (TRD) is a severe public health problem and a condition uncommonly addressed by psychological therapies.
Michel A. Reyes-Ortega, Jorge Barraca, Jessica Zapata-Téllez, Alejandra M. Castellanos-Espinosa, Joanna Jiménez-Pavón   +4 more
doaj   +1 more source

Transdiagnostic treatment of bipolar disorder and comorbid anxiety using the Unified Protocol for Emotional Disorders: A pilot feasibility and acceptability trial [PDF]

, 2017
BACKGROUND Comorbid anxiety in bipolar disorder (BD) is associated with greater illness severity, reduced treatment response, and greater impairment. Treating anxiety in the context of BD is crucial for improving illness course and outcomes. The current
Baek, Ji Hyun, Barlow, David H., Bernstein, Emily E., Deckersbach, Thilo, Ellard, Kristen K., Hearing, Casey, Nierenberg, Andrew A., Sylvia, Louisa G.   +7 more
core   +1 more source

Hydrogel‐Based Functional Materials: Classifications, Properties, and Applications

Advanced Materials Technologies, EarlyView.
Conductive hydrogels have emerged as promising materials for smart wearable devices due to their outstanding flexibility, multifunctionality, and biocompatibility. This review systematically summarizes recent progress in their design strategies, focusing on monomer systems and conductive components, and highlights key multifunctional properties such as
Zeyu Zhang, Zao Cheng, Patrizio Raffa
wiley   +1 more source

Atypical Antipsychotics and Other Therapeutic Options for Treatment of Resistant Major Depressive Disorder

Pharmaceuticals, 2010
Antidepressant therapies, such as selective serotonin reuptake inhibitors (SSRIs), are current first-line treatments for Major Depressive Disorder. However, over 50% of treated patients show an inadequate response to initial antidepressant therapy.
Allan H. Young, Holly MacPherson, Rubo J. Seo   +2 more
doaj   +1 more source

A Wireless, Implantable, and Stretchable Device for Optogenetic Modulation (WISDOM) in the Central and Peripheral Nervous Systems

Advanced Optical Materials, EarlyView.
WISDOM, a wireless, implantable, and stretchable optogenetic platform inspired by climbing tendrils, integrates a 3D helical interconnect and customizable µ‐LEDs for precise, long‐term neuromodulation across the brain, peripheral nerves, and organs in freely behaving animals, enabling system‐level studies and therapeutic exploration of complex ...
Kuoying Qiao, Ge Wu, Yi Cao, Yiyong Wu, Chongyang Sun, Jianyu Huang, Shuyang Yang, Cheng Zhong, Haihan Zhou, Yi Lu   +9 more
wiley   +1 more source