Results 51 to 60 of about 3,916,339 (374)

Adequate screening of youngsters for depressive characteristics [PDF]

, 2013
Introduction. In order to set up an effective early-detection of depressive symptoms in youngsters, the current study aims to investigate whether two measure moments of the Children's Depression Inventory (CDI) improve screening and whether a multi ...
Braet, Caroline, Roelofs, Jeffrey, Stark, Kevin, Theuwis, Lotte, Vandevivere, Eva   +4 more
core   +2 more sources

Failure of hippocampal deactivation during loss events in treatment-resistant depression [PDF]

, 2015
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging and behavioural studies of major depressive ...
Blair A. Johnston, Cavanagh, David Christmas, J. Douglas Steele, Keith Matthews, Ma, Serenella Tolomeo, Victoria Gradin, Zhang   +8 more
core   +2 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Understanding the role of P2X7 in affective disorders—are glial cells the major players? [PDF]

, 2015
Pathophysiology associated with several psychiatric disorders has been linked to inflammatory biomarkers. This has generated a theory of major depressive disorders as an inflammatory disease.
Jenkins, Trisha A., Spencer, Sarah J., Stokes, Leanne   +2 more
core   +2 more sources

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group

bioRxiv, 2019
Major depressive disorder (MDD) is associated with an increased risk of brain atrophy, aging-related diseases, and mortality. We examined potential advanced brain aging in adult MDD patients, and whether this process is associated with clinical ...
Laura K. M. Han, R. Dinga, T. Hahn, C. Ching, L. Eyler, L. Aftanas, M. Aghajani, A. Aleman, B. Baune, K. Berger, I. Brak, Geraldo Busatto Filho, A. Carballedo, Colm G. Connolly, B. Couvy-Duchesne, Kathryn R. Cullen, U. Dannlowski, C. Davey, D. Dima, F. Duran, V. Enneking, E. Filimonova, S. Frenzel, T. Frodl, C. H. Fu, B. Godlewska, I. Gotlib, H. Grabe, N. Groenewold, D. Grotegerd, O. Gruber, G. Hall, B. Harrison, S. Hatton, M. Hermesdorf, I. Hickie, T. Ho, N. Hosten, A. Jansen, Claas Kähler, T. Kircher, B. Klimes-Dougan, B. Krämer, A. Krug, J. Lagopoulos, Ramona Leenings, F. Macmaster, G. MacQueen, A. McIntosh, Q. McLellan, K. Mcmahon, S. Medland, B. Mueller, B. Mwangi, E. Osipov, M. Portella, E. Pozzi, L. Reneman, J. Repple, Pedro G. P. Rosa, M. Sacchet, P. Sämann, K. Schnell, A. Schrantee, E. Simulionyte, J. Soares, J. Sommer, Dan J Stein, O. Steinsträter, Lachlan T. Strike, S. Thomopoulos, M. van Tol, I. Veer, R. Vermeiren, H. Walter, N. J. van der Wee, S. V. D. van der Werff, H. Whalley, N. Winter, K. Wittfeld, M. Wright, Mon-Ju Wu, H. Völzke, Tony T. Yang, Vasileios Zannias, G. Zubicaray, G. Zunta-Soares, C. Abé, M. Alda, O. Andreassen, E. Bøen, C. Bonnín, Erick Jorge Canales-Rodríguez, D. Cannon, X. Caseras, Tiffany M Chaim-Avancini, T. Elvsåshagen, P. Favre, S. Foley, J. Fullerton, J. Goikolea, B. Haarman, T. Hajek, C. Henry, J. Houenou, F. Howells, M. Ingvar, R. Kuplicki, B. Lafer, M. Landén, R. Machado-Vieira, U. Malt, C. Mcdonald, P. Mitchell, Leila Nabulsi, M. Otaduy, B. Overs, M. Polosan, E. Pomarol-Clotet, J. Raduà, M. Rive, G. Roberts, H. Ruhé, R. Salvador, S. Sarró, T. Satterthwaite, J. Savitz, A. Schene, P. Schofield, Mauricio Serpa, K. Sim, M. Soeiro-de-Souza, Ashley N. Sutherland, H. Temmingh, G. Timmons, A. Uhlmann, E. Vieta, D. Wolf, M. Zanetti, N. Jahanshad, P. Thompson, D. Veltman, B. Penninx, A. Marquand, J. Cole, L. Schmaal   +145 more
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

A retrospective analysis to estimate the healthcare resource utilization and cost associated with treatment-resistant depression in commercially insured US patients.

PLoS ONE, 2020
ObjectiveThe economic burden of commercially insured patients in the United States with treatment-resistant depression and patients with non-treatment-resistant major depressive disorder was compared using data from the Optum Clinformatics™ claims ...
Gang Li, Ling Zhang, Allitia DiBernardo, Grace Wang, John J Sheehan, Kwan Lee, Johan Reutfors, Qiaoyi Zhang   +7 more
doaj   +2 more sources

Anxiety and depression: One, two or three disorders? [PDF]

Psihologija, 2004
The study deals with theoretical psychiatric proposals about relations between anxiety and depressive disorders. Three theoretical positions developed on the basis of numerous evidence on relationship of anxiety and depressive disorders: unitaristic ...
Novović Zdenka
doaj   +1 more source

Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group

Molecular Psychiatry, 2016
The neuro-anatomical substrates of major depressive disorder (MDD) are still not well understood, despite many neuroimaging studies over the past few decades.
L. Schmaal, D. Hibar, P. Sämann, G. Hall, B. Baune, N. Jahanshad, J. Cheung, T. V. Erp, D. Bos, M. Ikram, M. W. Vernooij, W. Niessen, W. Niessen, H. Tiemeier, H. Tiemeier, A. Hofman, K. Wittfeld, H. Grabe, Deborah Janowitz, R. Bülow, M. Selonke, H. Völzke, D. Grotegerd, U. Dannlowski, U. Dannlowski, V. Arolt, N. Opel, W. Heindel, H. Kugel, D. Hoehn, M. Czisch, B. Couvy-Duchesne, B. Couvy-Duchesne, M. Rentería, Lachlan T. Strike, M. Wright, Natalie T. Mills, Natalie T. Mills, G. Zubicaray, K. Mcmahon, S. Medland, N. Martin, N. Gillespie, R. Goya-Maldonado, O. Gruber, B. Krämer, S. Hatton, J. Lagopoulos, I. Hickie, T. Frodl, T. Frodl, A. Carballedo, Eva-Maria Frey, L. V. Velzen, B. Penninx, M. V. Tol, N. Wee, C. Davey, B. Harrison, B. Mwangi, B. Cao, J. Soares, I. Veer, Henrik Walter, D. Schoepf, B. Zurowski, C. Konrad, E. Schramm, C. Normann, K. Schnell, M. Sacchet, I. Gotlib, G. MacQueen, B. Godlewska, T. Nickson, A. McIntosh, A. McIntosh, M. Papmeyer, M. Papmeyer, H. Whalley, J. Hall, J. Hall, J. Sussmann, Meng Li, M. Walter, L. Aftanas, I. Brack, N. Bokhan, N. Bokhan, N. Bokhan, P. Thompson, D. Veltman   +91 more
semanticscholar   +1 more source