Results 51 to 60 of about 457,701 (285)

Potential of niacin skin flush response in adolescent depression identification and severity assessment: a case-control study

open access: yesBMC Psychiatry
Background The diagnosis of adolescent Depressive Disorder (DD) lacks specific biomarkers, posing significant challenges. This study investigates the potential of Niacin Skin Flush Response (NSFR) as a biomarker for identifying and assessing the severity
Jie Feng   +12 more
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Suicidal Ideation and Its Associated Factors Among Patients with Major Depressive Disorder at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia

open access: yesNeuropsychiatric Disease and Treatment, 2021
Elyas Adamsu Basha,1 Bethelehem Taye Mengistu,1 Nigus Alemnew Engidaw,1 Abate Dargie Wubetu,1 Assalif Beyene Haile2 1Department of Nursing, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Midwifery, College of ...
Basha EA   +4 more
doaj  

An Out‐of‐Place Etiology: Recognizing FMR1 Premutation in the Memory Clinic

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The FMR1 gene premutation (55–200 CGG repeats) is usually associated with a wide range of symptoms and phenotypes within the Fragile X‐tremor/ataxia syndrome (FXTAS), but may also manifest as predominant or isolated cognitive decline. We describe three male patients referred for progressive cognitive impairment and behavioral changes. Standard
Guido Greco   +7 more
wiley   +1 more source

Risk of Major Depression Associated with Excessive Daytime Sleepiness in Apneic Individuals

open access: yesClocks & Sleep
Considering the frequent co-occurrence of major depressive disorder and excessive daytime sleepiness in apneic individuals, this study aimed to explore the relationship between excessive daytime sleepiness and the risk of developing major depressive ...
Matteo Conenna   +4 more
doaj   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

Bipolar and major depressive disorders: associations with serum zonulin levels and rs2070937 polymorphism

open access: yesBMC Psychiatry
Background The underlying pathophysiology of bipolar disorder and major depressive disorder is not fully understood. Inflammation is increasingly recognized as a contributing factor. The gut plays a central role in this process.
Ozgur Baykan   +3 more
doaj   +1 more source

The Mediating Role of Self-Efficacy in Sleep Disorder and Depressive Symptoms Among Chinese Caregivers of Stroke Inpatients: A Structural Equation Modeling Analysis

open access: yesNeuropsychiatric Disease and Treatment, 2021
Longjuan Cong,1 Yanhong Ju,2 Ling Gui,3 Bo Zhang,1 Fangyan Ding,3 Changqing Zou4 1Department of Social Medicine, College of Health Management, China Medical University, Shenyang, Liaoning, People’s Republic of China; 2Section of Statistics, 4th People’s ...
Cong L   +5 more
doaj  

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons   +31 more
wiley   +1 more source

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