Effects of Fumarprotocetraric Acid, a Depsidone from the Lichen Cladonia verticillaris, on Tyrosinase Activity [PDF]
Orbital: The Electronic Journal of Chemistry, 2017 Lichens are widely distributed around the world. Their phenolic compounds, consisting mainly of depsides and depsidones, have been extensively studied for important biological activities.
Luiz Fabrício Gardini Brandão +6 more
doaj +6 more sources
The depsidones from marine sponge-derived fungus Aspergillus unguis IB151 as an anti-MRSA agent: Molecular docking, pharmacokinetics analysis, and molecular dynamic simulation studies [PDF]
Saudi Pharmaceutical Journal, 2023 Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging nosocomial pathogen among hospitalized patients, with high morbidity and mortality rates. The discovery of a novel antibacterial is urgently needed to address this resistance problem.
Dian Handayani +8 more
doaj +3 more sources
Characterization of the depsidone gene cluster reveals etherification, decarboxylation and multiple halogenations as tailoring steps in depsidone assembly [PDF]
Acta Pharmaceutica Sinica B, 2023 Depsides and depsidones have attracted attention for biosynthetic studies due to their broad biological activities and structural diversity. Previous structure‒activity relationships indicated that triple halogenated depsidones display the best anti ...
Jiafan Yang +4 more
doaj +4 more sources
Structural Characterization and Assessment of Anti-Inflammatory Activities of Polyphenols and Depsidone Derivatives from Melastoma malabathricum subsp. normale [PDF]
Molecules, 2022 The roots of Melastoma malabathricum subsp. normale (D. Don) Karst. Mey have been used in traditional ethnic medicine systems in China to treat inflammation-triggered ailments, such as trauma, toothache, and fever.
Rui-Jie He +6 more
doaj +4 more sources
Depside and Depsidone Synthesis in Lichenized Fungi Comes into Focus through a Genome-Wide Comparison of the Olivetoric Acid and Physodic Acid Chemotypes of Pseudevernia furfuracea [PDF]
Biomolecules, 2021 Primary biosynthetic enzymes involved in the synthesis of lichen polyphenolic compounds depsides and depsidones are non-reducing polyketide synthases (NR-PKSs), and cytochrome P450s.
Garima Singh +3 more
doaj +4 more sources
Brominated Depsidones with Antibacterial Effects from a Deep-Sea-Derived Fungus Spiromastix sp. [PDF]
Marine DrugsEleven new brominated depsidones, namely spiromastixones U-Z5 (1–11) along with five known analogues (12–16), were isolated from a deep-sea-derived fungus Spiromastix sp. through the addition of sodium bromide during fermentation.
Zequan Huang +7 more
doaj +4 more sources
Bioproduction of Depsidones for Pharmaceutical Purposes [PDF]
, 2011 الأشنات هي تكافلات حميمة وطويلة الأجل محددة من الطحالب الضوئية أو البكتيريا الزرقاء والفطريات غيرية التغذية التي انضمت لتشكيل كيان بيولوجي جديد مختلف عن مكوناته الفردية (جالون وكارديش، 1995). ينتج الكلوروليكين بشكل أساسي مواد فينولية فريدة من نوعها، ديبيد، ديبسيدون وبعض ثنائي بنزوفيوران، مثل أحماض اليوزنيك (Huneck & Yoshimura، 1996)، التي لا تنتجها ...
Carlos Vicente +2 more
core +5 more sources
Depsidone Derivatives and a Cyclopeptide Produced by Marine Fungus Aspergillus unguis under Chemical Induction and by Its Plasma Induced Mutant [PDF]
Molecules, 2018 A new depsidone derivative (1), aspergillusidone G, was isolated from a marine fungus Aspergillus unguis, together with eight known depsidones (2‒9) and a cyclic peptide (10): agonodepside A (2), nornidulin (3), nidulin (4), aspergillusidone F (5 ...
Wen-Cong Yang +6 more
doaj +2 more sources
Naphthalenones and Depsidones from a Sponge-Derived Strain of the Fungus Corynespora cassiicola [PDF]
Molecules, 2016 Two new naphthalenones, corynenones A and B (1 and 2), and one new depsidone, corynesidone E (3), together with one known depsidone, corynesidone A (4) and two known diphenyl ethers, corynethers A (5) and B (6), were isolated from the sponge-derived ...
Dong-Lin Zhao +5 more
doaj +2 more sources
Lichen-Derived Diffractaic Acid Inhibited Dengue Virus Replication in a Cell-Based System [PDF]
Molecules, 2023 Dengue is a mosquito-borne flavivirus that causes 21,000 deaths annually. Depsides and depsidones of lichens have previously been reported to be antimicrobials. In this study, our objective was to identify lichen-derived depsides and depsidones as dengue
Naphat Loeanurit +10 more
doaj +2 more sources