Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.Effect of lobaric acid on Wnt/β‐catenin pathway in breast cancer. ABSTRACT Lichen secondary metabolites with many remarkable biological activities are used in cancer treatments due to their low side effects and high anticancer potential. In particular, these metabolites constitute an interesting research area in cancer treatments due to their potential
Şeyda Nur Kalın +6 more
wiley +1 more source
Marine Drugs, 2015 Bioassay-guided evaluation shows that a deep sea-derived fungus, Spiromastix sp. MCCC 3A00308, possesses lipid-lowering activity. Chromatographic separation of a culture broth resulted in the isolation of 15 known depsidone-based analogues, labeled ...
Chongming Wu +8 more
doaj +1 more source
Notes on the circumscription of the lichens Lecanora leprosa and L. sulphurescens (Lecanoraceae, lichenised Ascomycotina) [PDF]
, 2013 Lecanora leprosa and L. sulphurescens are two commonly misidentified pantropical lichens. A detailed circumscription is presented to help overcome such difficulties. Both species contain a chemosyndrome of chlorodepsidones based on gangaleoidin.
Elix, John A., Lumbsch, Helge Thorsten
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A computational insight into acetylcholinesterase inhibitory activity of a new lichen depsidone [PDF]
, 2014 Acetylcholinesterase (AChE) inhibitors are yet the best drugs currently available for the management of Alzheimer's disease. The recent phytochemical investigation has led to the isolation of a new depsidone 1 with moderate AChE activity (1 mu g).
Ece, Abdulilah, Pejin, Boris
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Lichenochemical analysis and in vitro antioxidant activity of extracts and gyrophoric acid from lichen Umbilicaria grisea [PDF]
, 2023 This research investigates the chemical composition, total phenolic and flavonoid content, and antioxidant activity of acetone, methanol, and ethanol extracts of the lichen Umbilicaria grisea, and its major secondary metabolite, gyrophoric acid.
Kocovic, Aleksandar +5 more
core +1 more source
Lichen and Its Microbiome as an Untapped Source of Anti‐Biofilm Compounds
Chemistry &Biodiversity, Volume 22, Issue 4, April 17, 2025.Lichens and their associated fungi give rise to the evaluation of several extracts and compounds against biofilms. ABSTRACT Lichen substances have been first described in the 1870s, and around 10 000 compounds have been isolated and characterized. Most of them have been evaluated for their activity on planktonic microorganisms (bacteria and fungi ...
Marion Millot +4 more
wiley +1 more source
A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster [PDF]
, 2015 Recently, the Aspergillus terreus terrein gene cluster was identified and selected for development of a new heterologous expression system. The cluster encodes the specific transcription factor TerR that is indispensable for terrein cluster induction. To
Alberts +46 more
core +2 more sources
Conventional and innovative approaches to black fungi control for stone heritage preservation
IUBMB Life, Volume 77, Issue 3, March 2025.Abstract Black Meristematic Fungi (BMF) are characterized by a thick melanized cell wall and an isodiametric cellular expansion. BMF represent one of the most damaging groups of microorganisms causing the deterioration of outdoor exposed stone monuments mainly due to the formation of dark spots and patches leading to the darkening of their surface ...
Domenico Celi +2 more
wiley +1 more source
Chemical constituents of the bark of ryparosa kunstleri (Flacourtiaceae) [PDF]
, 1997 The bark of Ryparosa kunstleri yielded the triterpenes friedelin, trichadenic acid B, and the new 3B-p-coumaroyl trichadenic acid as its major constituents.
Shaari, Khozirah, Waterman, Peter G.
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Lichen-Derived Depsides and Depsidones Modulate the Nrf2, NF-κB and STAT3 Signaling Pathways in Colorectal Cancer Cells [PDF]
, 2021 Katarzyna Papierska +6 more
openalex +1 more source