Results 101 to 110 of about 5,200,905 (357)
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Pond, F. J., Beers, F. T.
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To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
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Approximation of Generalized Left Derivations
We need to take account of the superstability for generalized left derivations (resp., generalized derivations) associated with a Jensen-type functional equation, and we also deal with problems for the Jacobson radical ranges of left derivations (resp ...
Sheon-Young Kang, Ick-Soon Chang
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On derivations and generalized derivations of bitonic algebras
We introduce the notion of bitonic algebras as a generalization of dual BCCalgebras, and define the notion of (r,l)-derivations, (l,r)-derivations and generalized (r,l) and (l,r)-derivations on the bitonic algebras. Then we study the properties of the derivations and the generalized derivations on the bitonic algebras and the commutative ...
Yon, Y.H., Ayar Ozbal, S.
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Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
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Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
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On derivations of pseudo L-algebras [PDF]
In this article, the focus is on the study of derivations on two types of algebraic structures: pseudo L-algebras and pseudo CKL-algebras. For pseudo L-algebras, the notions of left and right derivations are introduced.
Yu Qian Guo, Xiao Long Xin
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This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
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In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
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