Results 101 to 110 of about 872,781 (311)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Notes on the characterization of derivations

open access: yes, 2012
Although the characterization of ring derivations has an extensive literature, up to now, all of the characterizations have had the following form: additivity and another property imply that the function in question is a derivation.
Gselmann, Eszter
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Soft derivative

open access: yesBoletim da Sociedade Paranaense de Matemática
This study presents a comprehensive investigation of soft and upper (lower) soft derivatives within the framework of Molodtsov’s soft set theory, extending it through the introduction of novel and complementary notions: left and right soft derivatives.
Enginoğlu, Serdar, Arslan, Burak
openaire   +2 more sources

Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance [PDF]

open access: bronze, 2007
N.J. Robertson   +5 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Some Centrally Extended Derivations on Banach Algebras

open access: yesMathematics
In this article, we consider centrally extended derivations on Banach algebras. We first establish the stability of centrally extended derivations on Banach algebras.
Ick-Soon Chang, Jaiok Roh
doaj   +1 more source

Study of MV-algebras via derivations

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2019
The main goal of this paper is to give some representations of MV-algebras in terms of derivations. In this paper, we investigate some properties of implicative and difference derivations and give their characterizations in MV-algebras.
Wang Jun Tao, She Yan Hong, Qian Ting
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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