Results 41 to 50 of about 14,414,832 (247)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
An inexact restoration derivative-free filter method for nonlinear programming [PDF]
, 2020 An inexact restoration derivative-free filter method for nonlinear programming is introduced in this paper. Each iteration is composed of a restoration phase, which reduces a measure of infeasibility, and an optimization phase, which reduces the ...
Vignau, Raúl Pedro +2 more
core
Journal of Inequalities and Applications, 2020 In this paper, we present a class of new derivative-free gradient type methods for large-scale nonlinear systems of monotone equations. The methods combine the RMIL conjugate gradient method, the strategy of hyperplane projection and the derivative-free ...
Xiaowei Fang
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
An optimal eighth order derivative free multiple root finding numerical method and applications to chemistry [PDF]
, 2023 [EN] In this paper, we present an optimal eighth order derivative-free family of methods for multiple roots which is based on the first order divided difference and weight functions.
Fiza Zafar +3 more
core +1 more source
Mathematical and Computational Applications, 2021 We present a local trust region descent algorithm for unconstrained and convexly constrained multiobjective optimization problems. It is targeted at heterogeneous and expensive problems, i.e., problems that have at least one objective function that is ...
Manuel Berkemeier, Sebastian Peitz
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
On a New Method for Derivative Free Optimization [PDF]
, 2011 A new derivative-free optimization method for unconstrained optimization of partially separable functions is presented. Using average curvature information computed from sampled function values the method generates an average Hessian-like matrix and uses
Frimannslund, Lennart, Steihaug, Trond
core
International Journal of Mathematics and Mathematical Sciences, 2022 In this study, the co-infection of HIV and cholera model has been developed and analyzed. The new fractional-order derivative is applied and the behavior of the solution is interpreted. The order of new generalized fractional-order derivative implication
Kumama Regassa Cheneke +2 more
doaj +1 more source