Results 51 to 60 of about 14,414,832 (247)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

A derivative-free method for bilevel optimization [PDF]

open access: yes, 2023
openThe goal is to design, under the assumption of having access to an approximation of the lower-level minimizer, derivative-free methods in order to solve the upper-level. The focus is on optimization with constraints, both in the smooth and non-smooth
BOJOVIC, MATIA
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Modified Steffensen Iterative Method with Fourth-order Convergence

open access: yesJournal of Harbin University of Science and Technology, 2017
A new fourth-order convergent iterative method formed by Newton’s method and Steffensen method is presented to solve nonlinear equations in this paper. The new iteration formula uses derivative of quadratic interpolation as substitute for derivative of
WEI Jia, HUANG Jia-yue
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

On Derivative-Free Optimisation Methods [PDF]

open access: yes, 2023
As part of the field of mathematical optimisation, derivative-free optimisation is the study of optimisation methods that are not granted full access to the derivative of the objective function. In this master's thesis, three derivative-free optimisation
Heeman, Pim
core  

A Second-Order Finite-Difference Method for Derivative-Free Optimization

open access: yesJournal of Mathematics
In this paper, a second-order finite-difference method is proposed for finding the second-order stationary point of derivative-free nonconvex unconstrained optimization problems.
Qian Chen, Peng Wang, Detong Zhu
doaj   +1 more source

Optimal Fourth-Order Methods for Multiple Zeros: Design, Convergence Analysis and Applications

open access: yesAxioms
Nonlinear equations are frequently encountered in many areas of applied science and engineering, and they require efficient numerical methods to solve. To ensure quick and precise root approximation, this study presents derivative-free iterative methods ...
Sunil Kumar   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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