Results 61 to 70 of about 14,414,832 (247)
An inexact restoration derivative-free filter method for nonlinear programming [PDF]
, 2017 An inexact restoration derivative-free filter method for nonlinear programming is introduced in this paper. Each iteration is composed of a restoration phase, which reduces a measure of infeasibility, and an optimization phase, which reduces the ...
Vignau, Raúl Pedro +2 more
core +1 more source
On the Convergence of a Kurchatov-Type Method for Solving Nonlinear Equations and Its Applications
AppliedMathA local and a semi-local convergence analysis are presented for the Kurchatov-type method to solve numerically nonlinear equations in a Banach space. The method depends on a real parameter. By specializing the parameter, we obtain methods already studied
Ioannis K. Argyros +2 more
doaj +1 more source
Algorithms for Molecular Biology, 2018 Background A profile-comparison method with position-specific scoring matrix (PSSM) is among the most accurate alignment methods. Currently, cosine similarity and correlation coefficients are used as scoring functions of dynamic programming to calculate ...
Kazunori D. Yamada
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
A derivative-free approach for large scale problems [PDF]
, 2022 Questa tesi si propone di illustrare e testare l'efficacia di un nuovo algoritmo per la risoluzione di problemi a larga scala senza l'utilizzo di ...
Roselli, Michele
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Calibrating the GAMIL3-1° climate model using a derivative-free optimization method [PDF]
Geoscientific Model DevelopmentParameterization in climate models often involves parameters that are poorly constrained by observations or theoretical understanding alone. Manual tuning by experts can be time-consuming, subjective, and prone to underestimating uncertainties. Automated
W. Liang +10 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source