Results 71 to 80 of about 67,632 (263)

Snap‐Through–Driven Liquid Crystal Elastomers for High‐Power Remote Microneedle Actuation Toward Smart Livestock Systems

Advanced Functional Materials, EarlyView.
A magnetically assisted snap‐through liquid crystal elastomer transforms photochemical deformation into a high‐power mechanical impulse, enabling remote microneedle actuation and highlighting its potential for future smart livestock intervention systems.
Chae Won Lee, Nankyung Kim, SeungHyun Park, Dae Seok Kim   +3 more
wiley   +1 more source

Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics

eLife
Allergic contact dermatitis (ACD), a prevalent inflammatory skin disease, is elicited upon repeated skin contact with protein-reactive chemicals through a complex and poorly characterized cellular network between immune cells and skin resident cells ...
Youxi Liu, Meimei Yin, Xiaoting Mao, Shuai Wu, Shuangping Wei, Shujun Heng, Yichun Yang, Jinwen Huang, Zhuolin Guo, Chuan Li, Chao Ji, Liu Hu, Wenjie Liu, Ling-juan Zhang   +13 more
doaj   +1 more source

Mechanical Programming of PEGDA‐β‐CD Polyrotaxane‐Based Hydrogels via Host–Guest Molecular Recognition

Advanced Functional Materials, EarlyView.
A mechanically programmable hydrogel for tissue engineering is developed by modulating the molecular threading density of poly(ethylene glycol) diacrylate‐β‐cyclodextrin (PEGDA‐β‐CD) polyrotaxane and combining it with β‐CD‐modified gelatin. The polyrotaxane‐guided transition from disordered pores to laminar microstructures enables precise tuning ...
Shiyi Chen, Xudan Xing, Haopu Su, Dominik Voll, Xiaohe Xu, Jiafeng Wan, Tongtong Cui, Christian W. Schmitt, Stefan Bräse, Peng Li, Patrick Théato   +10 more
wiley   +1 more source

Defective Induction of COX-2 Expression by Psoriatic Fibroblasts Promotes Pro-inflammatory Activation of Macrophages

Frontiers in Immunology, 2019
Fibroblasts play an important role as members of the innate immune system through the secretion of COX-2-derived inflammatory mediators such as prostaglandin E2 (PGE2).
Jorge Arasa, Jorge Arasa, María Carmen Terencio, María Carmen Terencio, Rosa María Andrés, Rosa María Andrés, Asunción Marín-Castejón, Asunción Marín-Castejón, Francisca Valcuende-Cavero, Francisca Valcuende-Cavero, Miguel Payá, Miguel Payá, María Carmen Montesinos, María Carmen Montesinos   +13 more
doaj   +1 more source

Human gingival fibroblast secretome accelerates wound healing through anti-inflammatory and pro-angiogenic mechanisms

npj Regenerative Medicine, 2020
Healing of the skin and oral mucosa utilises similar mechanisms of tissue repair, however, scarring and the rate of wound closure is vastly superior in the oral cavity suggesting differences between these two environments.
Parinaz Ahangar, Stuart J. Mills, Louise E. Smith, Stan Gronthos, Allison J. Cowin   +4 more
doaj   +1 more source

Hierarchical Collagen Nanofiber Gels Recapitulate a Physiologically Relevant Tumor Stromal Microenvironment

Advanced Healthcare Materials, EarlyView.
The collagen nanofiber (CNF) gel supports cancer cell culture, exhibiting cell morphology and cancer‐related protein expression similar to Matrigel. It offers a higher collagen concentration than commercial gels. Additionally, the CNF gel allows replication of the high elasticity of in vivo cancer tissue by controlling collagen fiber sizes, ranging ...
Naoko Sasaki, Tomoyuki Suezawa, Shiro Kitano, Ryohei Katayama, Michiya Matsusaki   +4 more
wiley   +1 more source

Magnetic gelatin-hesperidin microrobots promote proliferation and migration of dermal fibroblasts

Frontiers in Chemistry
Dermal fibroblasts play a crucial role in the formation of granulation tissue in skin wounds. Consequently, the differentiation, migration, and proliferation of dermal fibroblasts are considered key factors in the skin wound healing process.
Xuyan Sun, Hua Yang, Han Zhang, Weiwei Zhang, Chunyu Liu, Xiaoxiao Wang, Wenping Song, Lin Wang, Qingsong Zhao   +8 more
doaj   +1 more source

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Keratinocyte-driven dermal collagen formation in the axolotl skin

Nature Communications
Type I collagen is a major component of the dermis and is formed by dermal fibroblasts. The development of dermal collagen structures has not been fully elucidated despite the major presence and importance of the dermis. This lack of understanding is due
Ayaka Ohashi, Hirotaka Sakamoto, Junpei Kuroda, Yohei Kondo, Yasuhiro Kamei, Shigenori Nonaka, Saya Furukawa, Sakiya Yamamoto, Akira Satoh   +8 more
doaj   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source