Results 21 to 30 of about 4,965,242 (151)

Comparative secretome analysis of human follicular dermal papilla cells and fibroblasts using shotgun proteomics [PDF]

open access: yesBMB Reports, 2012
The dermal papilla cells (DPCs) of hair follicles are known tosecrete paracrine factors for follicular cells. Shotgun proteomicanalysis was performed to compare the expression profiles ofthe secretomes of human DPCs and dermal fibroblasts (DFs).In this ...
Chong Hyun Won   +12 more
doaj   +1 more source

GMP-Compliant Culture of Human Hair Follicle Cells for Encapsulation and Transplantation

open access: yesCell Transplantation, 2012
Human hair follicle cells, both bulge and dermal papilla cells, were isolated and cultured in a GMP cell factory, in order to obtain an in vitro hair follicle source for encapsulation end transplantation in alopecia regenerative cell therapy. An in vitro
Mario Marazzi   +12 more
doaj   +1 more source

Three New Dihydrophenanthrene Derivatives from Cymbidium ensifolium and Their Cytotoxicity against Cancer Cells

open access: yesMolecules, 2022
From the aerial parts of Cymbidium ensifolium, three new dihydrophenanthrene derivatives, namely, cymensifins A, B, and C (1–3) were isolated, together with two known compounds, cypripedin (4) and gigantol (5).
Tajudeen O. Jimoh   +7 more
doaj   +1 more source

Functional complexity of hair follicle stem cell niche and therapeutic targeting of niche dysfunction for hair regeneration

open access: yesJournal of Biomedical Science, 2020
Stem cell activity is subject to non-cell-autonomous regulation from the local microenvironment, or niche. In adaption to varying physiological conditions and the ever-changing external environment, the stem cell niche has evolved with multifunctionality
Chih-Lung Chen   +4 more
doaj   +1 more source

Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth

open access: yesFrontiers in Cell and Developmental Biology, 2021
Dermal papillae are a target of androgen action in patients with androgenic alopecia, where androgen acts on the epidermis of hair follicles in a paracrine manner.
Yufan Zhang   +10 more
doaj   +1 more source

Protective role of DDIT4-mediated autophagy in dermal papilla cells after oxidative stress injury

open access: yes陆军军医大学学报
Objective To explore the protective role of DNA damage induced transcription factor 4 (DDIT4) in oxidative stress injury in dermal papilla cells and its underlying mechanisms.
GAO Yuanyuan   +2 more
doaj   +1 more source

Effects of all-trans retinoic acid on goat dermal papilla cells cultured in vitro

open access: yesElectronic Journal of Biotechnology, 2018
Background: All-trans retinoic acid (ATRA), a vitamin A-derived active metabolite, exerts important functions in hair biology. Previous studies indicated that excess ATRA hampered hair follicle morphogenesis and cyclic regeneration in adulthood, but ...
Sen Ma, Guangxian Zhou, Yulin Chen
doaj   +1 more source

Trajectory of hiPSCs derived neural progenitor cells differentiation into dermal papilla-like cells and their characteristics

open access: yesScientific Reports, 2023
Dermal papilla cells (DPCs) play roles in key functions of the epidermis such as hair generation. The use of human induced pluripotent cells (hiPSCs) makes it possible to obtain DP-like cells and study the molecular mechanisms of DPC development during ...
Andrei Riabinin   +8 more
doaj   +1 more source

Preliminary evaluation of human hair follicle-derived dermal papilla cell characteristics

open access: yesHo Chi Minh City Open University Journal of Science - Engineering and Technology, 2023
Dermal Papilla Cells (DPCs) are mesenchymal cells residing at the base of the hair follicles. They play an important role in the hair cycle remodeling and hair follicle regeneration.
Dao Thi Thanh Thuy   +6 more
doaj   +1 more source

5α-Reductase Activity in Cultured Human Dermal Papilla Cells from Beard Compared with Reticular Dermal Fibroblasts [PDF]

open access: yes, 1990
The activity of 5α -reductase was assessed in cultured human beard dermal papilla cells and reticular dermal fibroblasts to elucidate the mechanism of androgen action in promoting the growth of beards in men. The monolayer was incubated with 50nM of [1,2-
Itami, Satoshi   +2 more
core   +1 more source

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