Results 31 to 40 of about 4,965,242 (151)

Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation

eLife, 2018
Mesenchymal condensation is a critical step in organogenesis, yet the underlying molecular and cellular mechanisms remain poorly understood. The hair follicle dermal condensate is the precursor to the permanent mesenchymal unit of the hair follicle, the ...
Leah C Biggs, Otto JM Mäkelä, Satu-Marja Myllymäki, Rishi Das Roy, Katja Närhi, Johanna Pispa, Tuija Mustonen, Marja L Mikkola   +7 more
doaj   +1 more source

miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells

Frontiers in Cell and Developmental Biology, 2020
The application of dermal papilla cells to hair follicle (HF) regeneration has attracted a great deal of attention. However, cultured dermal papilla cells (DPCs) tend to lose their capacity to induce hair growth during passage, restricting their ...
Yuxin Chen, Junfei Huang, Zhen Liu, Ruosi Chen, Danlan Fu, Lunan Yang, Jin Wang, Lijuan Du, Lihong Wen, Yong Miao, Zhiqi Hu   +10 more
doaj   +1 more source

FLIM for Evaluation of Difference in Metabolic Status between Native and Differentiated from iPSCs Dermal Papilla Cells

Cells, 2022
iPSCs and their derivatives are the most promising cell sources for creating skin equivalents. However, their properties are not fully understood. In addition, new approaches and parameters are needed for studying cells in 3D models without destroying ...
Alena Kashirina, Alena Gavrina, Artem Mozherov, Dmitriy Kozlov, Daria Kuznetsova, Ekaterina Vorotelyak, Elena Zagaynova, Ekaterina Kalabusheva, Aleksandra Kashina   +8 more
doaj   +1 more source

Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold

Biomolecules, 2020
Hair follicle dermal papilla cells (HFDPC) are a specialized cell population located in the bulge of the hair follicle with unique characteristics such as aggregative behavior and the ability to induce new hair follicle formation.
Nausika Betriu, Claire Jarrosson-Moral, Carlos E. Semino   +2 more
doaj   +1 more source

Hair follicle dermal cells: a morphological, behavioural and molecular study [PDF]

, 1995
Anatomy and smooth muscle a-actin expression in hair follicles from a variety of animal species (Mink, Polecat, Meerkat, Grey squirrel and stoat) was investigated. Smooth muscle ɑ-actin expression was related to follicle activity. Expression was greatest
Sleeman, Matthew Alexander, Sleeman, M
core  

Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells [PDF]

, 2006
Androgen exposure stimulates the growth of beard hair follicles. The follicle dermal papilla appears to be the site of androgen action; however, the molecular mechanisms that regulate this process are not well understood.
Kolpak, Meredith L., John A. Gourley, Gege Tan, Douglas Shander, Henry, James P., James P. Henry, Tan, Gege, Susan E. Rutberg, Shander, Douglas, Rutberg, Susan E., Meredith L. Kolpak, Gourley, John A.   +11 more
core   +1 more source

Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile Phenotype

Frontiers in Genetics, 2022
The dermal sheath (DS) is a population of mesenchyme-derived skin cells with emerging importance for skin homeostasis. The DS includes hair follicle dermal stem cells, which exhibit self-renewal and serve as bipotent progenitors of dermal papilla (DP ...
Juliane M. D. Ahlers, Cassandra Falckenhayn, Nicholas Holzscheck, Llorenç Solé-Boldo, Sabrina Schütz, Horst Wenck, Marc Winnefeld, Frank Lyko, Elke Grönniger, Annette Siracusa   +9 more
doaj   +1 more source

Molecular and cellular basis of Exogen and Anagen induction [PDF]

, 2007
The hair follicle has the unique capacity to pass through periods of growth, regression and rest before regenerating itself to restart the cycle. This dynamic cycling capacity enables animals to change their coats, and for hair length to be controlled at
Claire Alexandra Higgins,
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Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state

, 2022
Hair follicle stem cells are regulated by dermal papilla fibroblasts, their principal signaling niche. Overactivation of Hedgehog signaling in the niche dramatically accelerates hair growth and induces follicle multiplication in mice.
오지원
core   +1 more source

Dermal and epidermal cell functions in the growth and regeneration of hair follicles and other skin appendages [PDF]

, 1998
Epithelial-mesenchymal interactions are central to the development of skin and skin appendages in vertebrates. These interactions continue throughout adult life and underpin the cyclic growth and loss of hair in mammals. While the molecular basis of such
Gharzi, Ahmad
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