Results 141 to 150 of about 128,590 (274)

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

open access: yesSmall Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou   +8 more
wiley   +1 more source

TOPICAL CORTICOSTEROIDS AND TOIPICAL CALCINEURIN INHIBITORS IN STATE OF THE ART STRATEGY OF ATOPIC DERMATITIS TREATMENT

open access: yesВопросы современной педиатрии, 2006
Atopic dermatitis is a chronic allergic inflammation of skin. Topical corticosteroids, calcineurin inhibitors, skin emollients, antimicrobial preparations (in complicated cases), allergen and irritant elimination are used for topical treatment of atopic ...
A.V. Emelianov
doaj   +2 more sources

Faecalibacterium Diversity in the Gut Microbiome of Crohn's Disease Patients

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Faecalibacterium has recently garnered attention for its potential health implications. To better understand its role, we developed and assessed real‐time PCR assays for detecting and quantifying various Faecalibacterium species in human stool samples from both healthy individuals and Crohn's disease patients, either in flare or remission. The
Paul Mclellan   +16 more
wiley   +1 more source

Severe Skin Necrosis and Crusting Following Disseminated Herpes in a Kidney Transplant Patient: A Rare and Alarming Case

open access: yes
The Kaohsiung Journal of Medical Sciences, EarlyView.
Chung‐Ting Cheng   +3 more
wiley   +1 more source

Current Insights Into Individualized Diagnosis and Treatment of Allergic Rhinitis Based on Phenotype and Endotype

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu   +7 more
wiley   +1 more source

Two phase 3 trials of Dupilumab versus placebo in atopic dermatitis [PDF]

open access: yes, 2017
Dahdah, Lamia   +2 more
core   +1 more source

Treatment Satisfaction, Efficacy, and Safety of Delgocitinib Ointment for Atopic Dermatitis‐Induced Rash on the Face and Neck: Efficacy at Reducing Local Side Effects of Topical Steroid and Tacrolimus Ointment

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT This open‐label, single‐arm, multicenter clinical study evaluated the treatment satisfaction, efficacy, and safety of 0.5% delgocitinib ointment twice daily for 12 weeks, applied to face/neck lesions caused by ≥ 3 months use of topical steroids or tacrolimus ointment in patients with atopic dermatitis (AD).
Masatoshi Abe   +5 more
wiley   +1 more source

Intra‐Operative Onychoscopy of Subungual Epidermoid Inclusions

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Subungual epidermoid inclusions (SEI) are small epithelial inclusions, sometimes solid but mostly with central keratinization of the onycholemmal type without a granular layer. Exceptionally, they become large enough to produce symptoms such as pain or swelling of the nail bed, resulting in subungual keratosis, onycholysis, or a dystrophic ...
Grigorios Theodosiou   +2 more
wiley   +1 more source

Perceived Stigma and Mental Health Disorders Among Adults With Alopecia Areata Living in Japan

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Alopecia areata (AA) is a common disorder that causes hair loss and can significantly impact quality of life, which may be partially due to AA‐related stigma. Examining the impact of AA on psychosocial health is important for understanding the burden experienced by patients with AA.
Norimitsu Saito   +8 more
wiley   +1 more source

Use of Antidepressants Decreased After Initiation of ADHD Treatment in Adults—A Finnish Nationwide Register Study Describing Use of ADHD and Non‐ADHD Medication in People With and Without ADHD

open access: yesActa Psychiatrica Scandinavica, EarlyView.
Use of ADHD and non‐ADHD medication in people with and without ADHD in Finland. ABSTRACT Introduction ADHD is often associated with comorbid psychiatric conditions. Differential diagnosis between other conditions and ADHD is not always clear, and patients are sometimes initially treated for another disorder instead.
Elisa Westman   +8 more
wiley   +1 more source

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