Results 191 to 200 of about 128,590 (274)

Langerhans Cell Modulation in Atopic Dermatitis Is TLR2/SOCS1‐Dependent and JAK Inhibitor‐Sensitive

Allergy, EarlyView.
Constitutive exposure to TLR2 ligands can modify Langerhans cell (LC) activation capacity and outcome, being similar to LC in atopic dermatitis skin. While maturation marker and migration are impaired, the cytokine profile switches and favors atopic dermatitis‐related IL‐1β and IL‐18.
Yuxuan Deng, Nicole Leib, Sylvia Schnautz, Said Benfadal, Johannes Oldenburg, Thomas Bieber, Nadine Herrmann   +6 more
wiley   +1 more source

Treatment of Atopic Dermatitis with Upadacitinib in a Patient During Hepatitis C Activity Period. [PDF]

J Asthma Allergy
Huang J, Wang M, Gao XH, Zhang L.
europepmc   +1 more source

AI‐Based Objective Severity Assessment of Atopic Dermatitis Using Patient Photos in a Real‐World Setting: A Digital Biomarker Approach

Allergy, EarlyView.
Utako Okata‐Karigane, Masakazu Hirota, Chiaki Takahashi, Akihiro Miyagawa, Ryotaro Ako, Saeko Nakajima, Masaki Futamura, Satoru Yonekura, Yasushi Ogawa, Takenori Inomata, Tetsuo Ishikawa, Yoshihiro Ito, Katsunori Masaki, Sakura Sato, Norito Katoh, Hideaki Morita, Takeya Adachi   +16 more
wiley   +1 more source

Transcriptomic Analysis of Allergic Patch Test Reactions in Non‐Atopic Patients: A Comparative Study Across Multiple Allergens

Allergy, EarlyView.
This study investigated the immune mechanisms underlying allergic contact dermatitis (ACD) in response to four distinct allergens by using RNA sequencing in a cohort of 40 non‐atopic patients and 19 controls. A shared ACD imprinting across allergens showed strong innate and adaptive responses, dominated by type 1 immunity but with mixed immune ...
David Pesqué, Evelyn Andrades, Pau Berenguer‐Molins, Júlia Perera‐Bel, Miquel Clarós, Marta Bódalo‐Torruella, Mònica González‐Farré, Fernando Gallardo, Ramon M. Pujol, Ana M. Giménez‐Arnau   +9 more
wiley   +1 more source

Patients With Atopic Dermatitis Show Increased Clonal Hematopoiesis and Risk of Hematological Cancer

Allergy, EarlyView.
Verena Vogi, Emina Jukic, Robert Gruber, Andre Fiona, Deborah Minzaghi, Johannes Zschocke, Sandrine Dubrac   +6 more
wiley   +1 more source

Multiomics Analysis of the Response to Ritlecitinib in Alopecia Areata Subtypes and Correlation With Efficacy

Allergy, EarlyView.
Ritlecitinib modulated Type I/II immunity genes (CCL5, CD8A, GZMB, CCL13, CCL18, and IL13RA1), MoA genes (JAK3, ITK, and BTK), and upregulated hair keratins, with stronger effects in AAP than AT/AU. Baseline and longitudinal scalp and serum protein changes correlated with hair regrowth and disease improvement.
Li Xi, Elena Peeva, Yuji Yamaguchi, Zhan Ye, Alexandre Lejeune, Craig Hyde, Emma Guttman‐Yassky   +6 more
wiley   +1 more source

Drug Search and Design Considering Cell Specificity of Chemically Induced Gene Expression Profiles for Disease-Associated Tissues. [PDF]

Mol Inform
Yamanaka C, Iwata M, Kaitoh K, Yamanishi Y.   +3 more
europepmc   +1 more source

Role of Oxidative Stress and Antioxidants in the Course of Atopic Dermatitis. [PDF]

Int J Mol Sci
Kvedariene V, Vaskovic M, Semyte JB.
europepmc   +1 more source

The Aetiology of Elevated Total Serum Immunoglobulin E in Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä, Kaarina Kukkonen, Svetlana Vakkilainen   +2 more
wiley   +1 more source

At-Home Evaluation of Both Wearable and Touchless Digital Health Technologies for Measuring Nocturnal Scratching in Atopic Dermatitis: Analytical Validation Study.

J Med Internet Res
Avey S, Morris M, Sargsyan D, Lucas MV, O'Brisky A, Mosca K, Elias A, Fountoulakis N, Boukhechba M, Kok XH, Jain S, Oghbaie M, Manyakov NV, Wang M, Aguilar Z, Yieh L.   +15 more
europepmc   +1 more source