Results 111 to 120 of about 484,964 (356)

Arginine Metabolic Disruption Impairs Hair Regeneration via ROS‐Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia

Advanced Science, EarlyView.
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan, Guo Li, Yanji Chu, Junbo Zhang, Li Yang, Yujin Zhang, Fangfen Liu, Jiayun Li, Mengting Chen, Ben Wang, Zhixiang Zhao, Wei Shi, Yiya Zhang, Guangtong Deng, Xinwei Kuang, Hongfu Xie, Yufan Cheng, Zhili Deng, Ji Li, Yan Tang   +19 more
wiley   +1 more source

Bioinformatics‑Based Analysis Reveals Diagnostic Biomarkers and Immune Landscape in Atopic Dermatitis

Clinical, Cosmetic and Investigational Dermatology
Mingmei Yang,1 Xiaolei Zhang,1 Chao Zhou,2 Yuanyun Du,1 Mengyuan Zhou,1 Wenting Zhang1 1Department of Dermatology, Affiliated Changzhou Children’s Hospital of Nantong University, Changzhou, People’s Republic of China; 2Institute of Biomedical Engineering
Yang M, Zhang X, Zhou C, Du Y, Zhou M, Zhang W   +5 more
doaj  

Artificial Intelligence‐Driven Proteomics Identifies Plasma Protein Signatures for Diagnosis and Stratification of Behçet's Disease

Advanced Science, EarlyView.
Molecular and functional landscape of BD progression and severity based on in‐depth proteomics. Tree boosting machine learning models with favorable performance in BD diagnosis and stratification. Efficient biomarker panels for BD diagnosis and stratification. .
Linlin Cheng, Mansheng Li, Zhou Bai, Xiaobo Yu, Wenjie Zheng, Yongzhe Li, Yudong Liu   +6 more
wiley   +1 more source

Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg [PDF]

, 2007
Background: This paper describes the results of a feasibility study for a randomised controlled trial (RCT). Methods: Twenty-nine members of the UK Dermatology Clinical Trials Network (UK DCTN) expressed an interest in recruiting for this study.
Cox, Neil H., Meredith, Sarah, Nunn, Andrew, Reynolds, Nick, Savelyich, Boki S.P., Shipley, Debbie, Thomas, Kim S., UK Dermatology Clinical Trials Network (charity status), Williams, Hywel C.   +8 more
core   +1 more source

Acneiform dermatoses [PDF]

, 1998
Acneiform dermatoses are follicular eruptions. The initial lesion is inflammatory, usually a papule or pustule. Comedones are later secondary lesions, a sequel to encapsulation and healing of the primary abscess.
Jansen, Thomas, Plewig, G.
core   +1 more source

Corrigendum to “Self‐assembly Multifunctional DNA Tetrahedron for Efficient Elimination of Antibiotic‐Resistant Bacteria” https://doi.org/10.1002/agt2.402

Aggregate, EarlyView.
ABSTRACT Antibiotic resistance is a major challenge in the clinical treatment of bacterial infectious diseases. Herein, we constructed a multifunctional DNA nanoplatform as a versatile carrier for bacteria‐specific delivery of clinical antibiotic ciprofloxacin (CIP) and classic nanoantibiotic silver nanoparticles (AgNP). In our rational design, CIP was
Tiantian Wu, Yu Fu, Shuang Guo, Yanqiang Shi, Yuxin Zhang, Zhijin Fan, Bin Yang, Baoquan Ding, Yuhui Liao   +8 more
wiley   +1 more source

Biological and Bioinspired Vesicles for Wound Healing: Insights, Advances and Challenges

International Journal of Nanomedicine
Yingchao Zhao,1,* Tingrui Zhang,1,* Guan Lin Zhao,2,* Jiaye Lu,1 Xinyue Zhang,1 Yongxian Lai,1 Zhongjian Chen,1 Xiaofeng Ding,1 Zongguang Tai1 1Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai ...
Zhao Y, Zhang T, Zhao GL, Lu J, Zhang X, Lai Y, Chen Z, Ding X, Tai Z   +8 more
doaj  

Bilateral keratoprostheses in a patient with ocular mucous membrane pemphigoid. [PDF]

, 2019
Mucous membrane pemphigoid (MMP) with ocular involvement, also referred to as ocular cicatricial pemphigoid, is a rare, autoimmune blistering disease that can have devastating effects for patients.
Bromley, Jennifer, DeGrazia, Taryn, Feldman, Ron   +2 more
core  

Decoding Tattoo and Permanent Makeup Pigments: Linking Physicochemical Properties to Absorption, Distribution, Metabolism, and Elimination Profiles Using Quantitative Structure–Activity Relationship (QSAR)‐Based New Approach Methodologies (NAMs)

Advanced Intelligent Discovery, EarlyView.
This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod, Ajay Vikram Singh, Preeti Bhardwaj, Tulika Rai, Sweta Vijay Nakhale, Amruta Shelar, Rajendra Patil, Peter Laux, Andreas Luch, Christopher J. Osgood, Michael W. Stacey   +10 more
wiley   +1 more source

Association of the Monocyte-to-High Density Lipoprotein Ratio with the FRS and as a Predictor of Cardiovascular Risk in Individuals with Psoriasis Vulgaris

Clinical, Cosmetic and Investigational Dermatology
Xueqin Gu,1,* Hongmei Shen,2,* Jiafeng Jiang,1,* Ping Gu,2,* Peilong Liu,2 Zhenguo Zhao,3 Jinfang Ge1 1Department of Dermatology, The Second People’s Hospital of Nantong, Nantong, Jiangsu Province, People’s Republic of ...
Gu X, Shen H, Jiang J, Gu P, Liu P, Zhao Z, Ge J   +6 more
doaj