Results 81 to 90 of about 639,141 (400)

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina   +9 more
wiley   +1 more source

Novel tretinoin 0.05% lotion for the once-daily treatment of moderate-to-severe acne vulgaris in a preadolescent population. [PDF]

open access: yes, 2019
BackgroundAcne vulgaris (acne) is a common skin condition in children and adolescents. Efficacy of tretinoin is well documented in studies that included pediatric patients (12-18 years of age). With acne routinely presenting in younger patients, data are
Bhatt, Varsha   +4 more
core   +1 more source

Bilirubin Sensing Using Organic Electrochemical Transistors: Role of Gate Materials and Operational Parameters

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores PEDOT:PSS‐based OECTs as sensitive bilirubin sensors, revealing that polarizable gate electrodes (Au, Pt, glassy carbon) enable detection while non‐polarizable Ag/AgCl gates suppress response. Operational parameters modulate current direction, suggesting complex interfacial dynamics.
Yunjia Song, Sihui Xu, Onur Parlak
wiley   +1 more source

Virtual Clinical Trials: Perspectives in Dermatology

open access: yesDermatology, 2020
Background: The cost of developing a new drug is approximately USD 2.6 billion, and over two-thirds of the total cost is embedded in the clinical-testing phase.
Z. Ali, J. Zibert, S. Thomsen
semanticscholar   +1 more source

A case of new-onset vitiligo in a patient on tofacitinib and brief review of paradoxical presentations with other novel targeted therapies [PDF]

open access: yes, 2020
With recent advancements in the understanding of vitiligo pathogenesis, Janus kinase (JAK) inhibitors have emerged as a promising new treatment modality, but their effects remain incompletely elucidated.
Alikhan, Mujahed   +4 more
core  

Injectable Deep Eutectic Solvent‐Based Ionic Gel With Rapid Gelation and Broad Hemostatic Functionality

open access: yesAdvanced Healthcare Materials, EarlyView.
An injectable deep eutectic solvent‐based ionic gel is developed for rapid in situ gelation and broad‐spectrum hemostatic functionality. The material combines high mechanical strength, strong tissue adhesion, and antibacterial activity, demonstrating potential as an advanced biofunctional gel for emergency bleeding control and wound care.
Jia‐Yu Yang   +13 more
wiley   +1 more source

Expert consensus on clinical treatment dilemmas in elderly patients with atopic dermatitis

open access: yesPifu-xingbing zhenliaoxue zazhi
Atopic dermatitis (AD) is a common chronic, recurrent, inflammatory skin disease. With the aging of the global population, the prevalence of atopic dermatitis is increasing in the elderly (>60 years old).
Dermatology Branch of Guangdong Elder Health Care Association
doaj   +1 more source

Evaluating cultural competency and patient satisfaction in an urban dermatology clinic. [PDF]

open access: yes, 2017
Cultural competency continues to gain increased attention in medicine. Not only does it play a significant role in the delivery of health care and patient outcomes, but it also remains a major determinant of patient satisfaction.
Keller, Matthew   +2 more
core   +1 more source

Long-term safety and efficacy of trifarotene 50 μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne. [PDF]

open access: yes, 2020
BackgroundTreatment for both facial and truncal acne has not sufficiently been studied.ObjectivesTo evaluate the long-term safety and efficacy of trifarotene in both facial and truncal acne.MethodsIn a multicentre, open-label, 52-week study, patients ...
Ahmad, F   +11 more
core  

Cell‐Stress‐Free Percutaneous Bioelectrodes

open access: yesAdvanced Materials, EarlyView.
A structurally adaptive soft microneedle bioelectrode is developed with an effervescent sacrificial core that dissolves after insertion, leaving an ultrathin and highly compliant electrode integrated with skin. This design enables ultra‐flexible, cell‐stress‐free, stable, and high‐fidelity electrophysiological monitoring under dynamic conditions such ...
Jungho Lee   +14 more
wiley   +1 more source

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