Results 231 to 240 of about 193,828 (307)

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

Advanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura, Hiroyoshi Y. Tanaka, Mayu Ohira, Haruko Ohta‐Okano, Reika Nakamura, Yu Seno, Saaya Yara, Sakura Fujita, Daichi Shibata, Masaya Yamamoto, Shinichi Toyooka, Kensuke Osada, Horacio Cabral, Atsushi Masamune, Mitsunobu R. Kano   +14 more
wiley   +1 more source

Effect of Tecar Therapy in the Treatment of Skin Flaccidity and Localized Abdominal Fat-Clinical and Controlled Study. [PDF]

Dermatol Res Pract
de Almeida S, Santiago IB, Santi Martignago CC, Nishioka MA, Brassolatti P, Franco Dorigatti JH, Chieregato F, Araruna Alves AC, Queiroga Farias SL, Meyer PF, Ricardo de Souza J.   +10 more
europepmc   +1 more source

Physicochemical and Mechanical Characterization of Commercial Collagen‐Based Wound Dressings

Advanced NanoBiomed Research, EarlyView.
Commercial collagen‐based wound dressings are systematically compared to reveal how porous architecture governs hydration‐driven swelling and mechanical adaptation. Distinct structure–function relationships are identified, showing that wet‐state elasticity and conformability emerge from material composition and processing rather than manufacturer ...
Davide V. Verdolino, David M. Warde, Helen A. Thomason, Kimberly A. Mace, Sarah H. Cartmell   +4 more
wiley   +1 more source

Integrated Evaluation of Contaminant Profiles, Detection Techniques, and Management Strategies for Tannery Sludge

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This review article critically examines the environmental and health hazards of tannery sludge (TS), a complex by‐product of the leather tanning industry. TS is characterized by a diverse array of contaminants, including heavy metals like chromium, organic pollutants such as polycyclic aromatic hydrocarbons (PAHs), volatile organic compounds ...
Yashar Aryanfar, Ali Keçebaş, Soheil Hassanzadeh, Arash Nourbakhsh Sadabad, Farhan Lafta Rashid, Shabbir Ahmad, Ahmed Hendy, Hafiz M. Irfan, Shaban Mousavi Ghasemlou, Julio Blanco Fernandez, Jorge Luis Garcia Alcaraz   +10 more
wiley   +1 more source

A Case of Nevus of Ota Associated with Agminated Blue Nevus. [PDF]

Clin Cosmet Investig Dermatol
Xie X, Chen J, Zhou X, Zhu H, Ma S.
europepmc   +1 more source

Wound Repair Using PVA–CA Electrospun Dressings and Cold Plasma In Vivo

Journal of Applied Polymer Science, EarlyView.
In vivo wound healing evaluation of different treatments in a murine excisional wound model. (a) Representative photographs of wound closure at 3, 7, and 14 days post‐treatment for the different groups: Control, PVA‐CA, PVA‐CA‐Ag, NTP, PVA‐CA‐NTP, and PVA‐CA‐Ag‐NTP. (b) Experimental design showing six treatment groups with n = 18 wounds per group.
Jonalba M. Pereira, Emilia A. L. S. Arisawa, Antônio L. M. Maia‐Filho, José F. Silva, Nicoly Alves, Carolina H. da‐Silveira, Lucia Vieira   +6 more
wiley   +1 more source

Clinicopathological Analysis of 40 Cases of Extramammary Paget Disease: A Retrospective Study. [PDF]

Clin Cosmet Investig Dermatol
Zhang Q, Lv H, Chang J.
europepmc   +1 more source

The revision of baphetids from the Middle Pennsylvanian of the Czech Republic: Morphology, ontogeny, palaeoecology, and the reassessment of the phylogeny of Baphetoidea

The Anatomical Record, EarlyView.
Abstract The baphetoids represent a clade of the Carboniferous stem‐tetrapods (Middle Mississippian—Middle Pennsylvanian) with a characteristic extension of the orbits into antorbital vacuities, which formed keyhole‐shaped openings on the skull. The more derived baphetids were crocodile‐like piscivores frequently occurring in coal‐bearing lacustrine ...
Pavel Barták, Martin Ivanov, Boris Ekrt
wiley   +1 more source

Menopause and Dermal White Adipose Tissue Depletion: Mechanistic Links, Adipogenesis, and Regenerative Therapeutic Replacement. [PDF]

J Cosmet Dermatol
Widgerow AD, Ziegler ME, Shafiq F.
europepmc   +1 more source

Functional anatomy, jaw mechanisms, and feeding behavior of Dunkleosteus terrelli (Placodermi, Arthrodira)

The Anatomical Record, EarlyView.
A new musculoskeletal reconstruction and revision of the cranio‐mandibular anatomy of the Devonian arthrodire placoderm Dunkleosteus terrelli from a comparative and functional anatomical perspective. Dunkleosteus is a specialized arthrodire with many specializations for feeding on large vertebrates, and many of its features are part of broader ...
Russell K. Engelman, Robert K. Carr, Kate Trinajstic, Zerina Johanson, Oleg A. Lebedev   +4 more
wiley   +1 more source