Results 51 to 60 of about 122,885 (307)

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

The Association of Keloid Site with its Histopathological Features: an Analytical Observational Study

open access: yesBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology)
Background: Keloid is a growth of fibrous tissue in the wound tissue of susceptible individuals. This tissue extends beyond the boundaries of the previous wound.
Wibisono Nugraha   +5 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

TDP-43 Cytoplasmic Translocation in the Skin Fibroblasts of ALS Patients

open access: yesCells, 2022
Diagnosis of ALS is based on clinical symptoms when motoneuron degeneration is significant. Therefore, new approaches for early diagnosis are needed.
Miguel A. Rubio   +5 more
doaj   +1 more source

Aging Model for Unexposed Human Dermis

open access: yes, 1979
Young human dermis is charterized by the presence of many fibroblasts with distended endoplasmic reticulum, extensive Golgi bodies, and orderly and “clean”-appearing groundwork.
Montagna, William, Carlisle, K.S.
core   +1 more source

Active Learning‐Accelerated Discovery of Fibrous Hydrogels with Tissue‐Mimetic Viscoelasticity

open access: yesAdvanced Functional Materials, EarlyView.
Active learning accelerates the design of fibrous hydrogels that mimic the viscoelasticity of native tissues. By integrating multi‐objective optimization and closed‐loop experimentation, this approach efficiently identifies optimal formulations from thousands of possibilities and decouples elasticity and viscosity. The resulting hydrogels offer tunable
Zhengkun Chen   +11 more
wiley   +1 more source

Understanding Fibroblast Heterogeneity in Form and Function

open access: yesBiomedicines, 2023
Historically believed to be a homogeneous cell type that is often overlooked, fibroblasts are more and more understood to be heterogeneous in nature. Though the mechanisms behind how fibroblasts participate in homeostasis and pathology are just beginning
Jennifer B. Parker   +6 more
doaj   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

open access: yesAdvanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim   +9 more
wiley   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

Histological analysis of the dermal and hypodermal layers of the face and correlation with high-frequency 24 MHz ultrasonography and elastosonography

open access: yesEuropean Journal of Histochemistry
Knowledge of the structure of the face is of fundamental importance. In fact, the face is treated in many areas of medicine, from dermatology, to maxillofacial surgery, to otorhinolaryngology, to ophthalmology, etc.
Sheila Veronese   +4 more
doaj   +1 more source

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