Results 71 to 80 of about 124,551 (266)

Quantitative liquid storage by billiards‐like droplet collision on surfaces with patterned wettability

Droplet
There has been significant interest in researching droplet transport behavior on composite wetting surfaces. However, current research is primarily focused on modifying individual droplets and lacks an in‐depth investigation into high‐precision droplet ...
Minghao Li, Haoxu Yu, Zhirui Liu, Ziyue Gao, Faze Chen   +4 more
doaj   +1 more source

Quantum decoherence in a pragmatist view: Resolving the measurement problem [PDF]

, 2012
This paper aims to show how adoption of a pragmatist interpretation permits a satisfactory resolution of the quantum measurement problem. The classic measurement problem dissolves once one recognizes that it is not the function of the quantum state to ...
Healey, Richard
core   +1 more source

A framework for analyzing hyper-viscoelastic polymers

, 2017
Hyper-viscoelastic polymers have multiple areas of application including aerospace, biomedicine, and automotive. Their mechanical responses are therefore extremely important to understand, particularly because they exhibit strong rate and temperature ...
Siviour, Clive, Trivedi, Akash
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Collective wetting transitions of submerged gas‐entrapping microtextured surfaces

Droplet
Numerous natural and industrial processes entail the spontaneous entrapment of gas/air as rough/patterned surfaces are submerged under water. As the wetting transitions ensue, the gas diffuses into the water leading to the fully water‐filled state ...
Sankara Arunachalam, Himanshu Mishra
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Direct entropy determination and application to artificial spin ice

, 2012
From thermodynamic origins, the concept of entropy has expanded to a range of statistical measures of uncertainty, which may still be thermodynamically significant.
A Coniglio, A Dembo, A Wehrl, AG Schlijper, AG Schlijper, AJ Liu, AM Alsayed, B Cui, C Nisoli, Cristiano Nisoli, CS O’Hern, David M. Garand, EI Corwin, ER Weeks, ET Jaynes, F Ritort, G Möller, Jie Li, M Tanaka, O Penrose, Paul E. Lammert, Peter Schiffer, R Landauer, R Wang, RP Behringer, TM Cover, TS Majumdar, U Gasser, Vincent H. Crespi, VS Pande, WK Kegel, X Ke, Xianglin Ke, Y Qi   +33 more
core   +1 more source