Results 101 to 110 of about 1,939,299 (336)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
, 1996 We study some natural sets arising in the theory of ordinary differential equations in one variable from the point of view of descriptive set theory and in particular classify them within the Borel hierarchy.
Andretta, Alessandro, Marcone, Alberto
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Descriptive Set Theory and $ω$-Powers of Finitary Languages [PDF]
, 2020 Olivier Finkel, Dominique Lecomte
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
KOMUNIKASI PEMIMPIN PUSAT-DAERAH DI ERA REVOLUSI INDUSTRI 4.0
Jurnal Peurawi: Media Kajian Komunikasi Islam, 2019 Communication between central-regional leaders is a substance in building the Indonesian nation. The central leaders, both the President, the Minister, as well as the first and second echelon officials based in Jakarta, need a strategy in communicating ...
Abdul Rani Usman +2 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Humanities and Social Sciences, 2019 Information uncertainty in management systems is a subject of research of many scientific disciplines. Research concerning a quantitative modelling of uncertainty verging on mathematics, information technology, and logic is extremely important.
Rafał Mierzwiak
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Calidoscópio, 2011 Inspired on the British and American show Whose Line Is It Anyway?, where the public can create scenes for the actors to interpret, the Cia. Barbixas de Humor produces the performance Improvável – um espetáculo provavelmente bom (Unlikely – a likely good
Fábio José Rauen +1 more
doaj +1 more source