Results 1 to 10 of about 7,110 (229)
Desensitization: Overcoming the Immunologic Barriers to Transplantation [PDF]
Journal of Immunology Research, 2017 HLA (Human Leucocyte Antigen) sensitization is a significant barrier to successful kidney transplantation. It often translates into difficult crossmatch before transplant and increased risk of acute and chronic antibody mediated rejection after transplant.
Supreet Sethi +5 more
doaj +5 more sources
Excellent outcome after desensitization in high immunologic risk kidney transplantation
PLOS ONE, 2019 HLA-incompatible (HLAi) and ABO-incompatible (ABOi) kidney transplantation (KT) has been on the increase over the last decade. However, there are wide variations in outcomes from these procedures. In this study we evaluated the graft and patient outcomes in incompatible KT and non-sensitized KT.Patients who underwent KT between January 2012 and April ...
Jeong-Hoon Lim +10 more
openaire +5 more sources
Desensitization for the prevention of drug hypersensitivity reactions [PDF]
The Korean Journal of Internal Medicine, 2022 Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose.
Sung-Yoon Kang +2 more
doaj +1 more source
Prophylactic vaccinations management in patients undergoing allergen immunotherapy – a review
Family Medicine & Primary Care Review, 2022 Allergen immunotherapy (AIT) is the only casual method of allergy treatment. It is based on regular administration of a gradually increasing dose of an allergen to induce immunological tolerance to a particular sensitising factor. Due to proven efficacy,
Ewa Czerwińska +3 more
doaj +1 more source
Reumatismo, 2023 Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is the most common periodic fever syndrome in pediatric patients.
C. Granjo Morais +5 more
doaj +1 more source
Delivery options for sublingual immunotherapy for allergic rhinoconjunctivitis: clinical considerations for North America [PDF]
Rhinology Online, 2022 Background: Sublingual immunotherapy (SLIT) can be delivered via tablets (SLIT-T) or aqueous drops (SLIT-D). SLIT-D dosing recommendations using North American extracts were published in 2015.
Kent Lam +4 more
doaj +1 more source
HLA Desensitization in Solid Organ Transplantation: Anti-CD38 to Across the Immunological Barriers [PDF]
Frontiers in Immunology, 2021 The presence of anti-human leucocyte antigen (HLA) antibodies in the potential solid organ transplant recipient’s blood is one of the main barriers to access to a transplantation. The HLA sensitization is associated with longer waitlist time, antibody mediated rejection and transplant lost leading to increased recipient’s morbidity and mortality ...
Nizar Joher +5 more
openaire +5 more sources
Immunological mechanisms for desensitization and tolerance in food allergy [PDF]
Seminars in Immunopathology, 2012 Food allergy is a major public health concern in westernized countries, estimated to affect 5 % of children and 3-4 % of adults. Allergen-specific immunotherapy for food allergy is currently being actively evaluated, but is still experimental. The optimal protocol, in terms of the route of administration of the food, target maintenance dose, and ...
Rima Rachid +3 more
openaire +3 more sources
Oral desensitizing treatment in food allergy: clinical and immunological results [PDF]
Alimentary Pharmacology & Therapeutics, 2003 SummaryBackground : The possibility of inducing oral desensitization in patients with food allergy is still controversial and no standardized programmes are yet available.Aim : To evaluate the safety and efficacy of oral desensitization in patients with allergy induced by the most common food allergens.Methods : Fifty‐nine patients with food allergy ...
Patriarca, Giampiero +9 more
openaire +4 more sources
Oral Food Desensitization in Children With IgE-Mediated Cow's Milk Allergy: Immunological Changes Underlying Desensitization [PDF]
Allergy, Asthma & Immunology Research, 2017 This study aimed to evaluate the safety and efficacy to induce clinical desensitization to cow's milk (CM) of an oral immunotherapy (OIT) protocol in a pediatric population with cow's milk allergy (CMA). In addition, the immune responses against β-casein, of peripheral blood mononuclear cells (PBMCs) from CMA patients, before and after the protocol ...
Perezábad, Laura +5 more
openaire +5 more sources