Results 51 to 60 of about 4,383 (197)

Kinetics of Antibody Responses and Effector Cell Sensitivity After High Dose Birch Extract Nasal Challenge

Allergy, EarlyView.
High‐dose birch‐extract nasal challenge induced synchronous peaks at 4 weeks in serum specific IgE (sIgE) and basophil sensitivity. Mast cell sensitivity via tSPT and sIgG1 and sIgG4 responses peaked later, at 6–8 weeks. Preseasonal allergen exposure attenuated seasonal sIgE increase and prevented further rise in tSPT sensitivity.
N. J. Campion, S. Villazala‐Merino, C. Morgenstern, L. Nemec, V. Stanek, A. Tu, M. Zghaebi, J. Toth, R. Fröschl, T. Perkmann, M. Bastl, K. Gangl, S. Schneider, H. Breiteneder, R. Ristl, M. Focke‐Tejkl, R. Valenta, V. Niederberger‐Leppin, J. Eckl‐Dorna   +18 more
wiley   +1 more source

Efficacy and safety of a house dust mites allergoid in patients with allergic rhinitis—PROACAROS study: protocol for a randomized controlled trial

Trials
Background There is an important heterogeneity of the clinical research done to date for allergen immunotherapy (AIT). We plan to assess the safety and efficacy of a house dust mite (HDM) polymerized allergen extract mixture for allergic ...
Inmaculada Buendía-Jiménez, María Matas-Ros, Teresa Garriga-Baraut, Albert Roger-Reig, Ana Tabar-Purroy, on behalf of the PROACAROS investigator group   +5 more
doaj   +1 more source

Skin as an immune organ and clinical applications of skin-based immunotherapy

World Allergy Organization Journal, 2018
Background The prevalence of food allergy is increasing, and allergen avoidance continues to be the main standard of care. There is a critical need for safe and effective forms of immunotherapy for patients with food allergy as well as other allergic ...
J. Andrew Bird, Mario Sánchez-Borges, Ignacio J. Ansotegui, Motohiro Ebisawa, José Antonio Ortega Martell   +4 more
doaj   +1 more source

Desensitization With Imlifidase: Overcoming Immunological Barriers in Kidney Transplantation

Kidney Medicine
Highly sensitized patients without compatible living donors face prolonged waiting times for a transplant. Prioritization and desensitization strategies often prove insufficient because of logistical challenges, extended treatments, and increased infection risk.
Hernández-Velasco, Paul José, Gutiérrez Martínez, Eduardo, Polanco Fernández, Natalia, González Monte, Maria Esther, González-García, Celia, Mancebo Sierra, Esther, Andrés Belmonte, Amado   +6 more
openaire   +3 more sources

Basic and clinical immunology – 3016. Successful desensitization to oxaliplatin for metastic colorectal carcinoma [PDF]

World Allergy Organization Journal, 2013
Method In this case a premedication protocol of dexamethasone 10 mg + diphenhydramine 50 mg + famotidine 20 mg by mouth were administered 13 hours, 6 hours and 1 hour respectively prior to the infusion of 40 mg of oxaliplatin in 1:10000, 1:1000, 1:100, 1:10 graded dilutions. Each dilution was infused over 1 hour under close telemetry monitoring.
Buddiga, Praveen, Baz, Malik
openaire   +1 more source

Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper

Allergy, EarlyView.
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg, Julie van Waterschoot, Mathilde Moyaert, Adam Chaker, Philippe Gevaert, Jan Hagemann, Valérie Hox, Maarten Kleijwegt, Ludger Klimek, Devyani Lal, Juan Maza‐Solano, Oliver Pfaar, Fabio Simon Ryser, Michele Shiappoli, Diana Silva, Sanna Toppila‐Salmi, Johanna Wikstén, Sietze Reitsma, Laura Van Gerven   +18 more
wiley   +1 more source

Desensitization for hematopoietic stem cell transplantation: Case report

Brazilian Journal of Transplantation, 2020
Purpose: The presence of anti-human leukocyte antigen (HLA) antibodies has been correlated with graft failure in organ and tissue transplantation, demonstrating the importance of screening for antibodies before transplant.
Tatiana Schnorr Silva, Luciane Beatriz Kern, Ivaine Tais Sauthier Sartor, Mariana Pinto Pereira, Gabriela Oliveira Zavaglia, David Saitovitch, Lisandra Della Costa Rigoni, Claudia Caceres Astigarraga, Jorge Milton Neumann   +8 more
doaj  

TRADITIONAL AND CASCADE PLASMAPHERESIS IN ANTIBODY TITERS’ REDUCTION IN RENAL TRANSPLANT RECIPIENTS

Вестник трансплантологии и искусственных органов, 2014
Introduction. One of the current tasks of transplantology is to overcome «graft-host» immune confl ict. Partially this confl ict is caused by the presence of circulating pre-existing antibodies. Highly sensitized patients have a greater risk of rejection
A.V. Vatazin, A.B. Zulkarnayev, R.O. Kantarija, M. Krstich   +3 more
doaj   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

A prospective cohort study of ultra-rush subcutaneous immunotherapy in dust mite-induced allergic rhinitis

World Allergy Organization Journal
Background: Allergic rhinitis (AR) is a prevalent disease with a considerable global burden. Allergen immunotherapy (AIT) represents the cornerstone causal treatment for AR.
Yishan Xiong, MD, Wenqi Luo, MS, Hao Peng, MS, Li Shen, MS, Zhiqun Huang, MD, Jieqing Yu, MD, Jing Ye, MD, PhD   +6 more
doaj   +1 more source