Results 71 to 80 of about 4,383 (197)

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

Glomerular plasmalemma vesicle‐associated protein‐1 as an endothelial remodelling marker complementing C4d in chronic active antibody‐mediated rejection

Histopathology, EarlyView.
Glomerular plasmalemma vesicle‐associated protein‐1 (PV‐1/PLVAP) identifies dynamic endothelial remodelling in chronic active antibody‐mediated rejection (caABMR), complementing glomerular C4d, which reflects a static footprint of complement activation. Combined assessment of PV‐1 and C4d captures complementary dimensions of microvascular pathology and
Yuto Igarashi, Mayu Shimokawa, Kunio Kawanishi, Toshihito Hirai, Hiroshi Seino, Tomokazu Shimizu, Hideki Ishida, Toshio Takagi   +7 more
wiley   +1 more source

Distinct treatment response trajectories to allergen immunotherapy in allergic asthma and rhinitis: Insights from a multicenter study in routine clinical practice

World Allergy Organization Journal
Background: While allergen-specific immunotherapy (AIT) is recognized as an effective treatment, its efficacy varies widely. However, whether clinical response trajectories to AIT differ among individuals and influence its effectiveness has not been ...
Pingan Zhang, MD, Rundong Qin, PhD, Weixi Zhang, PhD, Yungang Yang, PhD, Huabin Li, PhD, Xiaoyan Dong, PhD, Yong He, PhD, Huiying Wang, PhD, Zhimin Chen, PhD, Liang Chen, PhD, Jinzhun Wu, PhD, Yanmin Bao, PhD, Man Tian, PhD, Guolin Tan, PhD, Jing Ye, PhD, Meiling Jin, PhD, Yi Liang, PhD, Kang Xu, PhD, Lijuan Mao, PhD, Qingqing Lv, PhD, Yi Zhang, PhD, Wanjun Wang, PhD, Jing Li, MD   +22 more
doaj   +1 more source

Feasibility and outcomes of kidney transplantation in patients with end‐stage kidney disease after haemopoietic stem cell transplantation

Internal Medicine Journal, EarlyView.
Abstract Background Advances in haemopoietic stem cell transplantation (HSCT) have improved long‐term survival, but they have also led to late complications, such as nephropathy. However, the safety and feasibility of kidney transplantation (KT) in patients with HSCT‐related end‐stage kidney disease (ESKD) remain unclear.
Bioh Kim, Seunghyeok Choi, Hanbi Lee, Hye‐Eun Yoon, Hohyung Nam, Silvia Park, Byung Ha Chung   +6 more
wiley   +1 more source

Cow’s Milk Desensitization in Anaphylactic Patients: A New Personalized-dose Method

Iranian Journal of Allergy, Asthma and Immunology, 2017
Cow’s milk allergy (CMA) is the most frequent food allergy in children and oral immunotherapy (OIT) is a promising approach for treatment of patients.
Delara Babaie, Mohammad Nabavi, Saba Arshi, Mehrnaz Mesdaghi, Zahra Chavoshzadeh, Mohammad Hasan Bemanian, Mitra Tafakori, Mehrdad Amirmoini, Hosein Esmailzadeh, Rasoul Molatefi, Mahsa Rekabi, Nadieh Akbarpour, Farimah Masoumi, Morteza Fallahpour   +13 more
doaj  

Intestinal transplantation in Australia: Progress, challenges and future directions

Internal Medicine Journal, EarlyView.
Abstract Background Intestinal transplant is a rare procedure reserved for patients with intestinal failure who cannot be sustained on total parenteral nutrition due to severe, life‐threatening complications. This study aims to describe the activity and outcomes of intestinal transplantation undertaken in Australia.
Brooke Chapman, Darren Wong, Graham Starkey, Marcos Perini, Jason Yap, Adam Testro   +5 more
wiley   +1 more source

Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran, Matjaž Fležar, Manuel Pedro Pereira   +2 more
wiley   +1 more source

Physical urticarias: mast cell disfunction. Preventive, diagnostic and therapeutical approach [PDF]

Einstein (São Paulo), 2007
Objective: To present and discuss the current classification of physicalurticarias based on immunologic and pathophysiological mechanisms.To describe clinical symptoms, triggering and worsening factors,different diagnostic tools, and to list the ...
Mario Geller
doaj  

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Correlation and Agreement Between Parent‐Report and Self‐Report Food Allergy Quality of Life Questionnaires After Oral Immunotherapy

Clinical &Experimental Allergy, EarlyView.
Sophie A. Rosser, Melanie Lloyd, Rachel L. Peters, Rushani Wijesuriya, Paxton Loke, Sarah E. Ashley, Adriana Chebar Lozinsky, Mimi L. K. Tang   +7 more
wiley   +1 more source