Results 61 to 70 of about 473,157 (249)

Desensitization With Imlifidase: Overcoming Immunological Barriers in Kidney Transplantation

Kidney Medicine
Highly sensitized patients without compatible living donors face prolonged waiting times for a transplant. Prioritization and desensitization strategies often prove insufficient because of logistical challenges, extended treatments, and increased infection risk.
Hernández-Velasco, Paul José, Gutiérrez Martínez, Eduardo, Polanco Fernández, Natalia, González Monte, Maria Esther, González-García, Celia, Mancebo Sierra, Esther, Andrés Belmonte, Amado   +6 more
openaire   +3 more sources

Botulinum Toxin for First Bite Syndrome: A Symptom‐Guided “Follow‐The‐Pain” Injection Strategy

Head &Neck, EarlyView.
ABSTRACT Background To evaluate botulinum toxin type A (BoNT‐A) for First Bite Syndrome (FBS) and assess a symptom‐guided “Follow‐the‐Pain” (FTP) injection strategy in patients with incomplete response to standard treatment. Methods Consecutive patients with postoperative FBS were treated with ultrasound‐guided intraparotid BoNT‐A injection.
Rosario Marchese‐Ragona, Gianmarco Giunta, Daniela Adamo, Elisabetta Zanoletti, Daniele Manfredini, Domenico Antonio Restivo   +5 more
wiley   +1 more source

Effects of rituximab dose on hepatitis B reactivation in patients with resolved infection undergoing immunologic incompatible kidney transplantation

Scientific Reports, 2018
Sensitized patients received desensitization therapy with rituximab for kidney transplantation. However, the impact of rituximab dose on hepatitis B virus (HBV) reactivation is unknown.
Juhan Lee, J. Y. Park, D. Kim, J. Lee, B. Kim, M. Kim, Soon Il Kim, Yu Seun Kim, K. Huh   +8 more
semanticscholar   +1 more source

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

The Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen, Carmen Esna, Camille Prigent, Anna Miles   +3 more
wiley   +1 more source

Efficacy and safety of a house dust mites allergoid in patients with allergic rhinitis—PROACAROS study: protocol for a randomized controlled trial

Trials
Background There is an important heterogeneity of the clinical research done to date for allergen immunotherapy (AIT). We plan to assess the safety and efficacy of a house dust mite (HDM) polymerized allergen extract mixture for allergic ...
Inmaculada Buendía-Jiménez, María Matas-Ros, Teresa Garriga-Baraut, Albert Roger-Reig, Ana Tabar-Purroy, on behalf of the PROACAROS investigator group   +5 more
doaj   +1 more source

Virtual Reality‐Based Vestibular Rehabilitation for Vestibular Migraine: A Randomized Trial

The Laryngoscope, EarlyView.
In this single‐blind randomized controlled trial, 40 patients with definite vestibular migraine were randomized 1:1 to home‐based vestibular rehabilitation alone (HB‐VestRehab, n = 20) or the same program plus eight clinic‐based virtual reality sessions (VR‐VestRehab, n = 20).
Gulce Kirazli, Hale Uzumcugil, Sumeyye Kapusizoglu, Ece Cinar, Huseyin Nezih Ozdemir, Gulsum Saruhan Durmaz, Isa Kaya, Tayfun Kirazli, Figen Gokcay, Nese Celebisoy   +9 more
wiley   +1 more source

Loss of tolerance 5 days after discontinuing sulphonamide introduced via desensitization in delayed reaction

Einstein (São Paulo), 2019
The fixed drug eruption is a non-immediate hypersensitivity reaction to drug, characterized by recurrent erythematous or violaceous, rounded, well-defined border plaques, which always appear in the same location every time the culprit drug is ...
Amanda Rocha Firmino Pereira, Marcelo Vivolo Aun, Nathália Coelho Portilho Kelmann, Antônio Abílio Motta, Jorge Kalil, Pedro Giavina-Bianchi   +5 more
doaj   +2 more sources

Basic and clinical immunology – 3016. Successful desensitization to oxaliplatin for metastic colorectal carcinoma [PDF]

World Allergy Organization Journal, 2013
Method In this case a premedication protocol of dexamethasone 10 mg + diphenhydramine 50 mg + famotidine 20 mg by mouth were administered 13 hours, 6 hours and 1 hour respectively prior to the infusion of 40 mg of oxaliplatin in 1:10000, 1:1000, 1:100, 1:10 graded dilutions. Each dilution was infused over 1 hour under close telemetry monitoring.
Buddiga, Praveen, Baz, Malik
openaire   +1 more source

HLA Mismatching Strategies for Solid Organ Transplantation - a Balancing Act

Frontiers in Immunology, 2016
HLA matching provides numerous benefits in organ transplantation including better graft function, fewer rejection episodes, longer graft survival, and the possibility of reduced immunosuppression.
Andrea A. Zachary, Mary S Leffell
doaj   +1 more source