Results 11 to 20 of about 18,140 (98)

Antimicrobial Desensitization: A Review of Published Protocols

Pharmacy, 2019
Antimicrobial desensitization represents a last-line option for patients with no alternative therapies, where the benefits of this intensive process must outweigh the potential harm from drug exposure. The goal of antimicrobial desensitization procedures
Daniel B. Chastain, Vanessa Johanna Hutzley, Jay Parekh, Jason Val G. Alegro   +3 more
doaj   +1 more source

DESENSITIZATION PROPERTIES OF P2X3 RECEPTORS SHAPING PAIN SIGNALLING

Frontiers in Cellular Neuroscience, 2013
ATP-gated P2X3 receptors are mostly expressed by nociceptive sensory neurons and participate in transduction of pain signals. P2X3 receptors show a combination of fast desensitization onset and slow recovery.
Rashid eGiniatullin, Andrea eNistri
doaj   +1 more source

One- versus 2-day aspirin desensitization in aspirin exacerbated respiratory disease: A quality improvement project

Journal of Allergy and Clinical Immunology: Global, 2023
Background: Current aspirin desensitization protocols for aspirin-exacerbated respiratory disease (AERD) require from 1 to 3 days to complete. Objective: Our aim was to assess the implementation of a 1-day versus 2-day aspirin desensitization protocol in
Emily Gansert, BS, Dan Morgenstern-Kaplan, MD, MS, Angela M. Donaldson, MD, Matthew A. Rank, MD, Alexei Gonzalez-Estrada, MD   +4 more
doaj  

Repeated cycles of high-dose intravenous immunoglobulin and plasmapheresis for treatment of late antibody-mediated rejection of renal transplants

Journal of the Formosan Medical Association, 2016
Intravenous immunoglobulin (IVIG) plays a central role in the treatment of antibody-mediated rejection (AMR) of renal allografts, but the treatment outcomes for late AMR (>6 months after transplantation) are poor.
Chih-Yuan Lee, Wei-Chou Lin, Ming-Shiou Wu, Ching-Yao Yang, Chi-Chuan Yeh, Meng-Kun Tsai   +5 more
doaj   +1 more source

Oral Desensitization to Penicillin for the Treatment of Pregnant Women with Syphilis: A Successful Program [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2018
Gestational syphilis is a prevalent disease in Brazil and other low and medium income countries. Desensitization to penicillin is recommended for pregnant women with syphilis who are allergic to β-lactams. This is a descriptive study utilizing outpatient
Jéssica Dallé, Mauro Cunha Ramos, Mirela Foresti Jimenez, Fernanda Garcia Escobar, Vicente Sperb Antonello   +4 more
doaj   +1 more source

Successful olaparib desensitization using a novel one-day protocol

Allergy, Asthma & Clinical Immunology, 2020
Background Olaparib is a revolutionary treatment for patients with ovarian and breast cancer. Currently, there is no established 1-day drug desensitization protocol for patients with olaparib type-1 hypersensitivity reactions despite well documented IgE ...
Rongbo Zhu, Stephen Welch, Hannah Roberts   +2 more
doaj   +1 more source

Rapid Desensitization with Autologous Sweat in Cholinergic Urticaria

Allergology International, 2011
Background: The majority of patients with cholinergic urticaria presents with strong hypersensitivity to autologous sweat. Patients with severe cholinergic urticaria are frequently resistant to H1 antagonists which are used in conventional therapies for ...
Takeshi Kozaru, Atsushi Fukunaga, Kumiko Taguchi, Kanako Ogura, Tohru Nagano, Masahiro Oka, Tatsuya Horikawa, Chikako Nishigori   +7 more
doaj   +1 more source

B Cell-Derived Extracellular Vesicles Reveal Residual B Cell Activity in Kidney Graft Recipients Undergoing Pre-Transplant Desensitization

Frontiers in Medicine, 2021
Background: Living-donor kidney transplant (LDKT) recipients undergoing desensitization for Human Leukocyte Antigen (HLA)-incompatibility have a high risk of developing antibody-mediated rejection (ABMR).
David Cucchiari, David Cucchiari, Valeria Tubita, Jordi Rovira, Jordi Rovira, Maria J. Ramirez-Bajo, Maria J. Ramirez-Bajo, Elisenda Banon-Maneus, Elisenda Banon-Maneus, Marta Lazo-Rodriguez, Natalia Hierro-Garcia, Francesc E. Borràs, Francesc E. Borràs, Francesc E. Borràs, Pedro Ventura-Aguiar, Gastón J. Piñeiro, Jaume Martorell, Lluís Peri, Mireia Musquera, Alexandre Hertig, Federico Oppenheimer, Federico Oppenheimer, Josep M. Campistol, Josep M. Campistol, Josep M. Campistol, Fritz Diekmann, Fritz Diekmann, Fritz Diekmann, Ignacio Revuelta, Ignacio Revuelta, Ignacio Revuelta   +30 more
doaj   +1 more source

Platinum desensitization therapy and its impact on the prognosis of ovary high-grade serous adenocarcinoma: a real world-data

Frontiers in Immunology
BackgroundTo examine the value of five-step platinum desensitization therapy in epithelial ovarian cancerMethodsA retrospective study was conducted on the high-grade serous adenocarcinoma of the ovary (HGSAO) patients who developed a platinum allergy ...
Kemin Li, Kemin Li, Rutie Yin, Rutie Yin
doaj   +1 more source

The desensitization gating of the MthK K+ channel is governed by its cytoplasmic amino terminus. [PDF]

PLoS Biology, 2008
The RCK-containing MthK channel undergoes two inactivation processes: activation-coupled desensitization and acid-induced inactivation. The acid inactivation is mediated by the C-terminal RCK domain assembly.
Mario Meng-Chiang Kuo, Innokentiy Maslennikov, Brent Molden, Senyon Choe   +3 more
doaj   +1 more source