Results 21 to 30 of about 139,872 (278)

Repeated cycles of high-dose intravenous immunoglobulin and plasmapheresis for treatment of late antibody-mediated rejection of renal transplants

open access: yesJournal of the Formosan Medical Association, 2016
Intravenous immunoglobulin (IVIG) plays a central role in the treatment of antibody-mediated rejection (AMR) of renal allografts, but the treatment outcomes for late AMR (>6 months after transplantation) are poor.
Chih-Yuan Lee   +5 more
doaj   +1 more source

Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors [PDF]

open access: yes, 1995
We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors ...
Cohen, B. N.   +5 more
core   +2 more sources

Successful drug desensitization in patients with delayed-type allergic reactions to anti-tuberculosis drugs

open access: yesInternational Journal of Infectious Diseases, 2018
Objective: To evaluate the outcomes of anti-tuberculosis drug desensitization. Methods: This was a retrospective study. Inclusion criteria were as follows: age >18 years, documented tuberculosis infection, a previous cutaneous allergic reaction to anti ...
Krittaecho Siripassorn   +2 more
doaj   +1 more source

Successful olaparib desensitization using a novel one-day protocol

open access: yesAllergy, Asthma & Clinical Immunology, 2020
Background Olaparib is a revolutionary treatment for patients with ovarian and breast cancer. Currently, there is no established 1-day drug desensitization protocol for patients with olaparib type-1 hypersensitivity reactions despite well documented IgE ...
Rongbo Zhu   +2 more
doaj   +1 more source

Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse [PDF]

open access: yes, 2017
Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in ...
Di Guilmi, Mariano Nicolás   +3 more
core   +1 more source

Oral Desensitization to Penicillin for the Treatment of Pregnant Women with Syphilis: A Successful Program [PDF]

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2018
Gestational syphilis is a prevalent disease in Brazil and other low and medium income countries. Desensitization to penicillin is recommended for pregnant women with syphilis who are allergic to β-lactams. This is a descriptive study utilizing outpatient
Jéssica Dallé   +4 more
doaj   +1 more source

Mechanisms of synaptic depression at the hair cell ribbon synapse that support auditory nerve function [PDF]

open access: yes, 2017
Inner hair cells (IHCs) in the cochlea are the mammalian phono-receptors, transducing sound energy into graded changes in membrane potentials, the so called “receptor potentials.” Ribbon synapses between IHCs and auditory nerve neurons are responsible ...
Goutman, Juan Diego
core   +1 more source

Rapid Desensitization with Autologous Sweat in Cholinergic Urticaria

open access: yesAllergology International, 2011
Background: The majority of patients with cholinergic urticaria presents with strong hypersensitivity to autologous sweat. Patients with severe cholinergic urticaria are frequently resistant to H1 antagonists which are used in conventional therapies for ...
Takeshi Kozaru   +7 more
doaj   +1 more source

Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity. [PDF]

open access: yes, 2019
TMEM16F is activated by elevated intracellular Ca2+, and functions as a small-conductance ion channel and as a phospholipid scramblase. In contrast to its paralogs, the TMEM16A/B calcium-activated chloride channels, mouse TMEM16F has been reported as a ...
Han, Tina W   +4 more
core   +2 more sources

Platinum desensitization therapy and its impact on the prognosis of ovary high-grade serous adenocarcinoma: a real world-data

open access: yesFrontiers in Immunology
BackgroundTo examine the value of five-step platinum desensitization therapy in epithelial ovarian cancerMethodsA retrospective study was conducted on the high-grade serous adenocarcinoma of the ovary (HGSAO) patients who developed a platinum allergy ...
Kemin Li, Kemin Li, Rutie Yin, Rutie Yin
doaj   +1 more source

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