Results 11 to 20 of about 91,740 (302)

Antimicrobial Desensitization: A Review of Published Protocols

Pharmacy, 2019
Antimicrobial desensitization represents a last-line option for patients with no alternative therapies, where the benefits of this intensive process must outweigh the potential harm from drug exposure. The goal of antimicrobial desensitization procedures
Daniel B. Chastain, Vanessa Johanna Hutzley, Jay Parekh, Jason Val G. Alegro   +3 more
doaj   +2 more sources

Modified Oral Metronidazole Desensitization Protocol

Allergy & Rhinology, 2014
The Center for Disease Control guidelines recommend desensitization to metronidazole in patients with trichomoniasis and hypersensitivity to metronidazole. There is only one published oral metronidazole desensitization protocol. The purpose of this study
Samantha R. Gendelman M.D., Lily C. Pien M.D., Ravi C. Gutta M.D., Susan R. Abouhassan M.D.   +3 more
doaj   +2 more sources

Molecular Mechanisms of P2X Receptor Desensitization [PDF]

Structural Dynamics
Extracellular ATP serves as a crucial signaling molecule, present in varying concentrations across diverse cellular environments. The P2X receptor (P2XR) family, which recognizes extracellular ATP, consists of seven subtypes (P2X1R - P2X7R) that form ...
Steven E. Mansoor
doaj   +2 more sources

The efficacy and psychophysiological correlates of dual-attention tasks in eye movement desensitization and reprocessing (EMDR) [PDF]

, 2011
This study aimed to investigate the psychophysiological correlates and the effectiveness of different dual-attention tasks used during eye movement desensitization and reprocessing (EMDR).
Christopher W. Lee, Lee, C.W., Drummond, P.D., Sarah J. Schubert, Schubert, S.J., Peter D. Drummond   +5 more
core   +1 more source

Findings of in vitro Analyses of Basophil Functions May Help Us Better Understand Drug Desensitization

Frontiers in Allergy, 2022
Drug hypersensitivity can be an important problem during pharmacological management of various diseases. Patients diagnosed as having a drug allergy usually need to avoid the offending drug, either temporarily or for life.
Masao Yamaguchi, Akiko Komiya, Maho Suzukawa, Rikiya Koketsu, Risa Shiragami, Motoyasu Iikura, Hiroyuki Nagase   +6 more
doaj   +1 more source

The evaluation of the desensitization effect of a desensitizing agent and desensitizing toothpastes in vitro.

Dental materials journal, 2020
This study was evaluating how three desensitizing toothpastes used at home influence the effect associated with desensitizing agents after application in the clinic. Fifty dentine disks measure it permeability and 32 dentine disks with similar permeability levels were selected.
HU, Meng-Long, ZHENG, Gang, JIANG, Ruo-Dan, HAN, Jian-Ming, ZHANG, You-Dong, LIN, Hong   +5 more
openaire   +2 more sources

The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor

Frontiers in Pharmacology, 2020
G protein coupled receptor (GPCR) kinases (GRKs) are key regulators of GPCR signaling. Canonical mechanism of GPCR desensitization involves receptor phosphorylation by GRKs followed by arrestin recruitment and uncoupling from heterotrimeric G protein ...
Emiliana Echeverría, Emiliana Echeverría, Maia Cabrera, Maia Cabrera, Valeria Burghi, Valeria Burghi, Máximo Sosa, Máximo Sosa, Sonia Ripoll, Sonia Ripoll, Agustín Yaneff, Agustín Yaneff, Federico Monczor, Federico Monczor, Carlos Davio, Carlos Davio, Carina Shayo, Natalia Fernández, Natalia Fernández   +18 more
doaj   +1 more source

DESENSITIZATION PROPERTIES OF P2X3 RECEPTORS SHAPING PAIN SIGNALLING

Frontiers in Cellular Neuroscience, 2013
ATP-gated P2X3 receptors are mostly expressed by nociceptive sensory neurons and participate in transduction of pain signals. P2X3 receptors show a combination of fast desensitization onset and slow recovery.
Rashid eGiniatullin, Andrea eNistri
doaj   +1 more source

Repeated cycles of high-dose intravenous immunoglobulin and plasmapheresis for treatment of late antibody-mediated rejection of renal transplants

Journal of the Formosan Medical Association, 2016
Intravenous immunoglobulin (IVIG) plays a central role in the treatment of antibody-mediated rejection (AMR) of renal allografts, but the treatment outcomes for late AMR (>6 months after transplantation) are poor.
Chih-Yuan Lee, Wei-Chou Lin, Ming-Shiou Wu, Ching-Yao Yang, Chi-Chuan Yeh, Meng-Kun Tsai   +5 more
doaj   +1 more source

Successful drug desensitization in patients with delayed-type allergic reactions to anti-tuberculosis drugs

International Journal of Infectious Diseases, 2018
Objective: To evaluate the outcomes of anti-tuberculosis drug desensitization. Methods: This was a retrospective study. Inclusion criteria were as follows: age >18 years, documented tuberculosis infection, a previous cutaneous allergic reaction to anti ...
Krittaecho Siripassorn, Kiat Ruxrungtham, Weerawat Manosuthi   +2 more
doaj   +1 more source