Results 41 to 50 of about 8,593 (205)

A randomised prospective comparison of equilibration point and changing gas composition during low-flow anaesthesia with sevoflurane vs desflurane

Indian Journal of Anaesthesia, 2019
Background and Aims: Safety and economy are the main concerns while using low- flow anaesthesia with newer inhalational agents. The main objective of this study was to use and compare 'equilibration time' of sevoflurane and desflurane after change-over ...
Pratibha Toal, Sheetal Chiplonkar, Pratik Panchal   +2 more
doaj   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

A randomised controlled trial comparing quality of recovery between desflurane and isoflurane inhalation anaesthesia in patients undergoing ophthalmological surgery at a tertiary hospital in South Africa (DIQoR trial)

BJA Open
Background: The patient's experience of their postoperative recovery is an important perioperative outcome, with the 15-item quality of recovery scale (QoR-15) recommended as a standardised outcomes measure.
Charlé Steyl, Hyla-Louise Kluyts
doaj   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Modulation of evoked GABAergic inhibition by desflurane.

, 2015
A. Evoked IPSCs elicited by a single stimulus before (Con) and during desflurane (Des). Gray traces indicate the average of the 15 superimposed traces. Bottom: Normalized average traces taken from upper panels. Monoexponential fitting (dashed lines) show
Albertino Bigiani (717905), Enrico Giuliani (717901), Daniela Gandolfi (416982), Egidio D’Angelo (416986), Federica Pellati (717903), Francesco P. Prencipe (717902), Alberto Barbieri (717904), Jonathan Mapelli (416983)   +7 more
core   +1 more source

Postoperative Recovery Outcomes for Obese Patients Undergoing General Anesthesia: A Meta-Analysis of Randomized Controlled Trials

Frontiers in Surgery, 2022
PurposeThis study was performed to assess the postoperative recovery outcomes in obese patients undergoing general anesthesia.MethodsThe eligible studies were identified from PubMed, EmBase, and the Cochrane library until December 2020. The standard mean
Zhen-Hua Hu, Zhe Liu, Gai-Fang Zheng, Zhan-Wen Li, Sheng-Qun Liu   +4 more
doaj   +1 more source

Flow‐controlled expiration improves gas exchange in anaesthetised horses undergoing orthopaedic surgery

Equine Veterinary Journal, Volume 58, Issue 4, Page 917-924, July 2026.
Abstract Background Flow‐controlled expiration (FLEX) has been shown to significantly enhance oxygenation in horses under laboratory conditions. Objective This study aims to corroborate these findings by evaluating the effects of FLEX on gas exchange in a randomised clinical trial involving a large population of clinical horses undergoing orthopaedic ...
Klaus Hopster, Joao Henrique Neves Soares, David Levine, Kyla Ortved, Bernd Driessen, Joaquin Araos   +5 more
wiley   +1 more source

Evaluation of the efficacy of desflurane with or without labetalol for hypotensive anesthesia in middle ear microsurgery

Journal of Anaesthesiology Clinical Pharmacology, 2017
Background and Aims: Hypotensive anesthesia technique is used to reduce intraoperative bleeding and to improve the visibility of the operative field. The aim was to evaluate the efficacy of desflurane with and without labetalol for producing hypotensive ...
Neha Gupta, Vandana Talwar, Smita Prakash, Achyut Deuri, Anoop Raj Gogia   +4 more
doaj   +1 more source

The comparative effects of desflurane and isoflurane on intraoperative cerebral hemodynamics, cardiovascular changes, and post-operative recovery in patients undergoing craniotomy for supratentorial tumors

Asian Journal of Medical Sciences, 2022
Background: Preserving hemodynamic stability, providing a slack brain, and enabling early recovery are the main criteria of neuroanesthesia. The most commonly used volatile anesthetic for neurosurgeries is isoflurane due to its favorable effects on ...
Titas Mandal , Maitreyee Mukherjee , Amita Acharjee , Soumya Chakrabarti   +3 more
doaj   +1 more source

Consistency and clarity of pharmacogenomic guidance in UK medicine patient information leaflets: A cross‐sectional analysis

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1934-1939, June 2026.
Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar, Chloe Ratcliffe, Videha Sharma, William G. Newman, Munir Pirmohamed, John McDermott   +5 more
wiley   +1 more source