Results 61 to 70 of about 8,593 (205)

Technical Feasibility of the RHYTHMIA Mapping System in Pediatric Patients Weighing Less Than 20Kg

Pacing and Clinical Electrophysiology, Volume 49, Issue 5, Page 523-530, May 2026.
ABSTRACT Background Catheter ablation in pediatric patients remains technically challenging. The RHYTHMIA high‐density mapping system is increasingly used in pediatric electrophysiology; however, procedural experience in patients weighing less than 20 kg is limited.
Wataru Sasaki, Taisuke Nabeshima, Kouta Nagaoka, Hitoshi Mori, Daisuke Kudo, Naomichi Tanaka, Tsukasa Naganuma, Masataka Narita, Kazuhisa Matsumoto, Yoshifumi Ikeda, Naokata Sumitomo, Kazuo Matsumoto, Ritsushi Kato   +12 more
wiley   +1 more source

The effects of desflurane on human platelet aggregation in vitro

, 2004
In view of the possible antiplatelet effects of general anesthetics, we investigated the in vitro effects of desflurane, a new inhalation agent, on platelet aggregation. For 15 patients who underwent elective operations, blood was sampled with desflurane
Karabiyik, LALE, Kaptan, K, Guner, D, Turkan, H, Beyan, C   +4 more
core   +1 more source

Induction of anaesthesia with desflurane and isoflurane in the rabbit

, 2001
The characteristics of two techniques of face-mask induction of desflurane anaesthesia (rapid or slow) were compared with the effects of slow isoflurane induction in five New Zealand White (NZW) rabbits.
Roughan JV; Flecknell PA; Antunes L; Orr H; Hedenqvist P
core   +2 more sources

Effects of desflurane on central and peripheral clock genes in mice

Di-san junyi daxue xuebao, 2019
Objective To investigate the effect and mechanism of the anesthetic drug, desflurane, on central and peripheral clock genes in mice. Methods C57BL/6J mice were anesthetized with different concentrations (3%, 4%, 6%, 7%, 9%) of desflurane, and then the ...
TIAN Hongni, ZHANG Erquan, LYU Shengqing, HUANG He, YANG Tiande   +4 more
doaj   +1 more source

Radioiodination of Two Carborane‐Based Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors and Their In Vitro and In Vivo Evaluation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich, Martin Ullrich, Cathleen Haase‐Kohn, Robert Wodtke, Sebastian Braun, Maximilian Molitor, Bettina Hofmann, Dieter Steinhilber, Klaus Kopka, Evamarie Hey‐Hawkins, Jens Pietzsch, Markus Laube   +11 more
wiley   +1 more source

Effect of desflurane anesthesia on flash visual evoked potential monitoring in patients undergoing spine surgery: study protocol for a randomized controlled trial

Trials
Background Flash visual evoked potentials (FVEPs) are a reliable method for protecting visual function during spine surgery in prone position. However, the popularization and application of FVEPs remain limited due to the unclear influence of various ...
Jiajia Ma, Jing Wang, Yun Li, Yuxuan Fu, Yang Li, Hui Qiao, Ruquan Han   +6 more
doaj   +1 more source

Comparison of maintenance, emergence and recovery characteristics of sevoflurane and desflurane in pediatric ambulatory surgery

Journal of Anaesthesiology Clinical Pharmacology, 2017
Background and Aims: Increasing number of pediatric ambulatory surgeries are being carried out in general anesthesia using supraglottic airways (SGAs). Literature comparing sevoflurane and desflurane for the maintenance of SGA-based anesthesia is limited.
Manish B Kotwani, Anila D Malde
doaj   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, Volume 13, Issue 23, 23 April 2026.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Surgical stimulation shifts EEG concentration-response relationship of desflurane

, 2001
BACKGROUND: Anesthesiologists routinely increase the delivered anesthetic concentration before surgical stimulation in anticipation of increased anesthetic requirement to achieve certain goals (e.g., amnesia, unconsciousness, and immobility ...
Hoeft, A., Koenen-Bergmann, M., Rehberg, B., Ropcke, H., Bouillon, Thomas, Bruhn, J.   +5 more
core   +1 more source

Assessing potential desflurane-induced neurotoxicity using nonhuman primate neural stem cell models

Experimental Biology and Medicine
Safety concerns about general anesthetics (GA), such as desflurane (a commonly used gaseous anesthetic agent), arose from studies documenting neural cell death and behavioral changes after early-life exposure to anesthetics and compounds with related ...
Cheng Wang, Leah E. Latham, Shuliang Liu, John Talpos, Tucker A. Patterson, Joseph P. Hanig, Fang Liu   +6 more
doaj   +1 more source