Results 51 to 60 of about 729,523 (281)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

An Improved Parameter Extraction Optimization Algorithm for RF Devices

open access: yesMicromachines
This paper proposes an improved parameter extraction optimization algorithm for radio frequency (RF) devices. The algorithm integrates parameter classification and correction, gradient-based performance handling, bias-aware updates, and group-based ...
Shengsen Yang, Zihan Xu, Kun Ren
doaj   +1 more source

Automatic Design of Microfluidic Gradient Generators

open access: yesIEEE Access, 2022
Concentration gradient generators are common components of microfluidic devices when specified mixing ratios have to be acquired. However, depending on their complexity, the creation of a suitable design is an elaborate task.
Gerold Fink   +4 more
doaj   +1 more source

CMOS array design automation techniques [PDF]

open access: yes
The design considerations and the circuit development for a 4096-bit CMOS SOS ROM chip, the ATL078 are described. Organization of the ATL078 is 512 words by 8 bits.
Feller, A., Lombardi, T.
core   +4 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Ensuring precision characteristics of equipment for rotary extrusion in the production of special technical products

open access: yesИзвестия высших учебных заведений. Поволжский регион:Технические науки
Background. The level of development of mechanical engineering significantly affects the economic potential and defense capability of the state. One of the main areas of mechanical engineering is the manufacture of products for aerospace technology ...
A.Yu. Ryazantsev   +3 more
doaj   +1 more source

A Contract-Based Methodology for Aircraft Electric Power System Design

open access: yesIEEE Access, 2014
In an aircraft electric power system, one or more supervisory control units actuate a set of electromechanical switches to dynamically distribute power from generators to loads, while satisfying safety, reliability, and real-time performance requirements.
Pierluigi Nuzzo   +7 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Automation Design and Analysis of the Wing Based on Aerodynamic and Structure Aspect Respectively [PDF]

open access: yes, 2014
Configuration/Geometry definition, grid generation/mashing, and modeling in wing design and analysis process usually spend much time to support calculation by computer program.
HADI, B. K. (BAMBANG)   +3 more
core  

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