Results 101 to 110 of about 4,347,183 (334)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 2144-2153, July 2025.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Design concept for bolted Glass

open access: yesChallenging Glass Conference Proceedings, 2010
For the design of load carrying glazing structures the connection technique plays an important role, as e.g. there are significant stress concentrations in the vicinity of holes that are subject to a point-like support of glass panes.
M. Baitinger, M. Feldmann
doaj   +1 more source

Computer-aided design of large-scale integrated circuits - A concept [PDF]

open access: yes, 1971
Circuit design and mask development sequence are improved by using general purpose computer with interactive graphics capability establishing efficient two way communications link between design engineer and system. Interactive graphics capability places
Schansman, T. T.
core   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 2109-2119, July 2025.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Investigating the adaptability and implementation of computational design methods in concept design taking plasterboard opportunities for dimensional coordination and waste reduction as a case study

open access: yesFrontiers of Architectural Research, 2023
Construction material offcuts is a data problem that can largely be avoided by dimensional coordination during concept design. Besides the environmental benefits, early phase coordination is beneficial to the overall design process as it integrates ...
Omar Majzoub   +2 more
doaj  

A novel integrated MADM method for design concept evaluation. [PDF]

open access: yesSci Rep, 2022
Chen Z, Zhong P, Liu M, Ma Q, Si G.
europepmc   +1 more source

Concept design of a fast sail assisted feeder container ship

open access: yes, 2010
An environmentally sustainable fast sail-assisted feeder-container ship concept, with a maximum speed of 25 knots, has been developed for the 2020 South East Asian and Caribbean container markets.
Burden, Aaron   +6 more
core   +1 more source

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