Results 141 to 150 of about 4,753,099 (348)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

An Integrated Decision Making Model for Evaluation of Concept Design

Acta Polytechnica, 2004
The Conceptual design phase generates various design concepts and these are then evaluated in order to identify the 'Best’ concept. Identifying the Best concept is important because much of the product life cycle cost is decided in this phase.
G. Green, G. Mamtani
doaj  

Down to the Bone: A Novel Bio-Inspired Design Concept. [PDF]

Materials (Basel), 2021
Buccino F, Aiazzi I, Casto A, Liu B, Sbarra MC, Ziarelli G, Vergani LM, Bagherifard S.   +7 more
europepmc   +1 more source

Design of Intelligent Graphene Facial Physiotherapy Instrument Based on Concept of Comprehensive Health

, 2022
Xin Li, Y. Zhang, Huabin Wang, Y Shi, Y An, P Huo, S Park, J Han, Y Yeon, N Kang, E Kim, B Suh, N Bowling, C Abendroth, A Ahmed, J Owusu, C Stewart, K Boahene, W Wang, T Wei, Y Zhang, Y Wang, Y Guo, Z Hong, M Wang, Y Tang, L Zheng, L Yin, S Narin, A Barutu, L Huang, G Yang, Y Shange, Y Zhao, Y Shange, Y Zhao, D O'leary   +36 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Efficient detailed design optimization of topology optimization concepts by using support vector machines and metamodels [PDF]

, 2019
Niclas Strömberg
openalex   +1 more source

Design and design of animaker-based video learning media on planet characteristics material to improve primary school students' understanding of science concepts

, 2023
Siti Aisyah, Jajang Bayu Kelana, Asep Kurnia Jayadinata   +2 more
openalex   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Wi-Fi Access Point Design Concept Targeting Indoor Positioning for Smartphones and IoT. [PDF]

Sensors (Basel), 2022
El-Gendy MS, Ashraf I, El-Hennawey S.
europepmc   +1 more source

PREFERENCES OF STUDENT RESIDENTS TOWARDS SUSTAINABILITY WITH THE CONCEPT OF BIOCLIMATIC DESIGN

, 2016
Adi Ainurzaman Jamaludin, Hazreena Hussein, Nila Keumala, Ati Rosemary Mohd Ariffin   +3 more
openalex   +2 more sources