Results 111 to 120 of about 4,260,477 (269)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Amplifying the politics in Service Design

open access: yes
Witnessing the speed of growth and reach in demand for service design (SD) confronts us to ask what neoliberal forces are behind this acceleration? Can services, systems and structures really improve at this velocity; what are we eroding and ignoring in ...
Akama, Yoko,   +5 more
core   +1 more source

Optimization, physical-chemical evaluation and healing activity of chitosan ointment [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2019
Context: Chitosan has received attention as a functional, sustainably renewable, nontoxic and biodegradable biopolymer for pharmaceutical applications such as healing agent.
Dania Pérez   +5 more
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Investigation of a Design Performance Measurement Tool for improving collaborative design during a design process

open access: yes, 2009
With rapid growth of global competition, the design process is becoming more and more complex due largely to cross-functional team collaboration, dynamic design processes, and unpredictable design outcomes.
Yin, Yuanyuan
core  

Estimating the Parameter of Direct Effects in Crossover Designs: The Case of 6 Periods and 2 Treatments

open access: yesStats
The present study investigates the derivation of optimal repeated measurement designs for two treatments, six periods, and n experimental units, focusing exclusively on the direct effects of the treatments.
Miltiadis S. Chalikias
doaj   +1 more source

STUDY ON THE ENERGETIC PARAMETERS IN A PHOTOTHERMIC SENSOR WITH BLACK POLYMERIC FILM [PDF]

open access: yesJournal of Fundamental and Applied Sciences, 2010
Renewable energies such as thermal solar energy are accessible energy hydrous for desalination water, recycling and hot water production. Heat is produced by greenhouse effect in the sensor.
A. Benmoussat   +3 more
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Reinventing Secondary School through design: An investigation of a Polytechnic High School Model focused on industry/community-driven design projects

open access: yes
This study examines the impact of a polytechnic high school model designed in collaboration with a research-intensive university and industry/community partners.
Lucas, Deana   +2 more
core   +1 more source

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