Results 121 to 130 of about 9,580,623 (304)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The effect of injector design on thrust- chamber erosion [PDF]
Relation between injector design and erosion of ablative and pyrolytic graphite thrust chamber ...
Rowley, R. W., Tyler, W. H.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
, 2012 It is claimed that a poster has about three seconds to catch the attention of a passer-by. The success of that poster teeters on those few seconds. If it fails to attract attention, then it is ineffective. However, if it catches the interest of its viewer, then half of the battle is won.
openaire +3 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
AerospaceCompared with conventional symmetric aircraft, the oblique-wing aircraft offers significant advantages across a wide speed range due to the variable oblique angle.
Zhuo Liu +4 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Uncertainty in the Design Stage of Two-Stage Bayesian Propensity Score Analysis
, 2018 The two-stage process of propensity score analysis (PSA) includes a design stage where propensity scores are estimated and implemented to approximate a randomized experiment and an analysis stage where treatment effects are estimated conditional upon the
Liao, Shirley, Zigler, Corwin
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Business Trends and Tendencies in Organization Design and Work Design Practice:Identifying Cause-and-Effect Relationships [PDF]
Current global business environment has a strong impact on theory and practice of organizations, as well as on working behavior of their employees. Increased complexity and competitiveness is changing settled ways of organizing and working.
Tomislav Hernaus
core +4 more sources