Results 101 to 110 of about 4,615,613 (282)

A preliminary study of the nonlinearity of adhesive point-fixings in structural glass facades

open access: yesJournal of Facade Design and Engineering, 2014
Corresponding author: Jonas Dispersyn, Laboratory for Research on Structural Models (LMO), Department of Structural Engineering, Faculty of Engineering and Architecture, Ghent University, Ghent, Belgium.
Jonas Dispersyn   +3 more
doaj  

Feasibility study of an induction motor rim drive for an aircraft boundary-layer-ingestion fan

open access: yesThe Journal of Engineering, 2019
This study presents a feasibility study for an induction motor rim drive to power aircraft boundary-layer-ingestion (BLI) fans. The design is developed from a BLI-fan specification for traditional aircraft architecture: the rotor is fastened to the rim ...
Alexander C. Smith   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A completely transparent, adhesively bonded soda-lime glass block masonry system

open access: yesJournal of Facade Design and Engineering, 2015
A pioneering, all transparent, self-supporting glass block facade is presented in this paper. Previously realized examples utilize embedded metal components in order to obtain the desired structural performance despite the fact that these elements ...
F. Oikonomopoulou   +3 more
doaj  

Structure design and finite element analysis of box type cargo picking robot clamp type end effector

open access: yesThe Journal of Engineering, 2019
At present, the box type cargo picking robot mostly adopts the sucker type end-effector in the logistics industry in china. In the light of the disadvantages and limitation of the complex heavy pneumatic devices used in the existing sucker type end ...
Zeyuan Li   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

OntoEng: A design method for ontology engineering in information systems [PDF]

open access: yes, 2009
This paper addresses the design problem relating to ontology engineering in the discipline of information systems. Ontology engineering is a realm that covers issues related to ontology development and use throughout its life span.
Al-Debei, MM, Fitzgerald, G
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Multi-objective optimization system for plant layout design (3rd report, Interactive multi-objective optimization technique for pipe routing design)

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
Plot plan drawings in the process and power industries are considered key decision-making documents for projects and are normally initiated in the pre-contract, conceptual, and developmental stages of a proposal.
Masakazu SHIRAKAWA, Masao ARAKAWA
doaj   +1 more source

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