Functionally heterogeneous porous scaffold design for tissue engineering [PDF]
, 2012 Most of the current tissue scaffolds are mainly designed with homogeneous porosity which does not represent the spatial heterogeneity found in actual tissues.
Khoda, AKM B. +2 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
TEC – Thin Environmental Cladding
Journal of Facade Design and Engineering, 2014 Corresponding author: Alan Tomasi, Group R&D Project Manager, Permasteelisa S.p.A., viale E. Mattei 21/23 | 31029 Vittorio Veneto, Treviso, Italy. Tel.: +39 0438 505207; E-mail: a.tomasi@permasteelisagroup.com; www.permasteelisagroup.com Permasteelisa ...
Alan Tomasi +4 more
doaj
Designing an online part-time Master of Philosophy with Problem Oriented Engineering [PDF]
, 2009 The paper reports on the application of Problem Oriented Engineering (POE) to the design of a highly innovative post-graduate research programme for the Open University, UK, a world leader in supported distance higher education.
Hall, Jon G., Rapanotti, Lucia
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Droplet dynamics on slippery surfaces: small droplet, big impact
Biosurface and Biotribology, 2019 The dynamic interaction of droplets with slippery surfaces is essential to various industrial applications, such as anti-icing, water-repellency or water-harvesting, anti-bacterial, and phase change heat transfer.
Yahua Liu +3 more
doaj +1 more source
DIDET: Digital libraries for distributed, innovative design education and teamwork. Final project report [PDF]
, 2008 The central goal of the DIDET Project was to enhance student learning opportunities by enabling them to partake in global, team based design engineering projects, in which they directly experience different cultural contexts and access a variety of ...
Breslin, C. +2 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Journal of Engineering, 2018 The magnetic-liquid suspension guide-way (MLSG) adopts the double support form of permanent magnetic suspension and hydrostatic pressure. It can greatly enhance the bearing capacity and rigidity of the guide-way system.
Jianhua Zhao +4 more
doaj +1 more source
"Why couldn't we do this more often?": exploring the feasibility of virtual and distributed work in product design engineering. [PDF]
Res Eng Des, 2022 Ferguson S +5 more
europepmc +1 more source