Results 41 to 50 of about 167,983,520 (303)

Designing experience

Future Hospital Journal, 2015
The report of the Future Hospital Commission of the Royal College of Physicians acknowledges that the principal challenge for health care organisations and professionals responsible for delivering medical services is to accept the fundamental requirement that patients must be treated with compassion, kindness and respect while having their physical and
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Cross-Over Design Experiment (Using SAS) [PDF]

, 2011
Cross-over experiments are a special class of repeated measures experiments. Up to now the repeated measures experiments that we have been investigating, are where the experimental unit is measured repeatedly after treatment.
Rahmawati, Rita
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Tidy dataset of the experimental design of the optimization of the alkali degumming process of Bombyx mori silk

Data in Brief, 2021
Silk fibroin is the structural fiber of the silk filament and it is usually separated from the external protein, named sericine, by a chemical process called degumming.
Alessio Bucciarelli, Gabriele Greco, Ilaria Corridori, Antonella Motta, Nicola M. Pugno   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Studio delle prestazioni di giunzioni incollate ibride [PDF]

Fracture and Structural Integrity, 2011
Le giunzioni ibride sono giunzioni in cui coesistono due differenti tipologie di giunzione, di cui una è l’incollaggio. L’articolo mostra i risultati di una campagna sperimentale volta a caratterizzare le prestazioni di giunti incollati ibridi in ...
F.Moroni
doaj  

Employment of factorial design to evaluate the organic loading and aeration of biological systems in the degradation of dairy wastewater

Revista Ambiente & Água, 2011
Among industries producing foodstuffs, the dairy industry is notable for producing great amount of wastewater and high water consumption. Organic loading treatment based on biological degradation is a preferential treatment for dairy wastewater and ...
Hélcio José Izário Filho, Juliana Sanches Carrocci, Rodrigo Fernando dos Santos Salazar   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source