Results 41 to 50 of about 1,282,652 (268)

Employment of factorial design to evaluate the organic loading and aeration of biological systems in the degradation of dairy wastewater

Revista Ambiente & Água, 2011
Among industries producing foodstuffs, the dairy industry is notable for producing great amount of wastewater and high water consumption. Organic loading treatment based on biological degradation is a preferential treatment for dairy wastewater and ...
Hélcio José Izário Filho, Juliana Sanches Carrocci, Rodrigo Fernando dos Santos Salazar   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Experimenting with a Design Experiment.

Revista internacional de sociologia, 2011
The design experiment is an experimental research method that aims to help design and further develop new (policy) instruments. For the development of a set of guidelines for the facilitation of citizens’ initiatives by local governments, we are experimenting with this method.
Bakker, Judith, Denters, Sebastianus A.H.   +1 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Innovative approaches to safe and sustainable material synthesis: Optimizing Ti3C2 MXene properties via design of experiments and chemometric analysis

Green Analytical Chemistry
MXenes are 2D materials that have received increasing attention since their first synthesis in 2011. They attracted attention due to their unique mechanical, electronic, optical and chemical properties, which make them suitable for multi-sectorial ...
Agnese Primieri, Rosangela Santalucia, Eugenio Alladio, Elena Corrao, Mattia Isola, Francesco Pellegrino, Valter Maurino   +6 more
doaj   +1 more source

Designing Blended Experiences

Designing Interactive Systems Conference 2021, 2021
The increasing ubiquity of interactions as a mix between digital content and physical objects and spaces, brings about new challenges for designers. There is a need to embed digital systems in physical places, whether those are existing physical structures or existing digital platforms.
Brian O'Keefe, Tom Flint, Michael Mastermaker, Miriam Sturdee, David Benyon   +4 more
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Analysis of parameters effects on crack breathing and propagation in shaft of rotor dynamic systems [PDF]

Materials Research, 2013
In this paper the design of experiment method is used to investigate and explain the effects of the rotor parameters on crack breathing and propagation in the shaft. Three factors are considered which have an influence on the behavior and the propagation
M. Serier, A. Lousdad, K. Refassi, A. Megueni   +3 more
doaj   +1 more source