Results 51 to 60 of about 1,535,464 (268)

Innovative approaches to safe and sustainable material synthesis: Optimizing Ti3C2 MXene properties via design of experiments and chemometric analysis

open access: yesGreen Analytical Chemistry
MXenes are 2D materials that have received increasing attention since their first synthesis in 2011. They attracted attention due to their unique mechanical, electronic, optical and chemical properties, which make them suitable for multi-sectorial ...
Agnese Primieri   +6 more
doaj   +1 more source

Surface Response Methodology-Based Mixture Design to Study the Influence of Polyol Blend Composition on Polyurethanes’ Properties

open access: yesMolecules, 2018
Polyurethanes are materials with a strong structure-property relationship. The goal of this research was to study the effect of a polyol blend composition of polyurethanes on its properties using a mixture design and setting mathematic models for each ...
Said Arévalo-Alquichire   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

CASE STUDIES OF USE OF DESIGN OF EXPERIMENTS IN MATERIAL RESEARCH

open access: yesJurnal Teknik Industri, 2003
The paper describes principles of factorial and fractional factorial design of experiments. The various ways of analysing data obtained by these procedures are shown via four case studies.
Salil Kumar Roy, I Nyoman Sutapa
doaj  

Optimal Designs to Develop and Support an Experimental Strategy on Innovation of Thermoforming Production Process

open access: yesStatistica, 2017
The experimental strategy developed thanks to the DOE methodology enhance innovation capability in the field of thermoforming production processes for active packaging. It is composed of three phases: i) material characterization, ii) production in pilot
Fabrizio Ronchi   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analysis of parameters effects on crack breathing and propagation in shaft of rotor dynamic systems [PDF]

open access: yesMaterials Research, 2013
In this paper the design of experiment method is used to investigate and explain the effects of the rotor parameters on crack breathing and propagation in the shaft. Three factors are considered which have an influence on the behavior and the propagation
M. Serier   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Formulation and Evaluation of Multidose Propofol Nanoemulsion Using Statistically Designed Experiments

open access: yesActa Chimica Slovenica, 2020
Despite of the clinical, scientific, and commercial development, many patients complain about pain on the intravenous injection of propofol. Present work was undertaken to develop a stable multi-dose propofol nano-emulsion using 32 full factorial design ...
Sidhartha Sankar Hota   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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