Results 61 to 70 of about 167,983,520 (303)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Barriers and Enablers of Co-design for Services [PDF]
, 2016 As interest towards co-design for services in the public sector and in companies is growing, the benefits and challenges of applying it in organisations have become a topical issue.
Pirinen, Antti
core
Design Education as a Catalyst for Change
, 2018 Designers play a role in shaping our world, both literally and figuratively. Human lives are spent interacting with designed artefacts, systems, and processes.
Mulder, Ingrid +9 more
core +1 more source
Acta Chimica Slovenica, 2020 Despite of the clinical, scientific, and commercial development, many patients complain about pain on the intravenous injection of propofol. Present work was undertaken to develop a stable multi-dose propofol nano-emulsion using 32 full factorial design ...
Sidhartha Sankar Hota +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The outline of the expert system for the design of experiment
Production Engineering Archives, 2018 The design of experiment (DoE) is a methodology originated from early 1920s when Fisher’s papers created the analysis of variance and first known experimental designs: latin squares.
Dwornicka Renata, Pietraszek Jacek
doaj +1 more source
Molecules, 2018 Polyurethanes are materials with a strong structure-property relationship. The goal of this research was to study the effect of a polyol blend composition of polyurethanes on its properties using a mixture design and setting mathematic models for each ...
Said Arévalo-Alquichire +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Workshop : an experiment of reflection on design game qualities and controversies
, 2013 How do various design games format and stage different collaborative inquiry, learning and reflection? At this hands-on workshop, we will collaboratively explore, relate and meta-reflect upon how different design (and learning) games can form part of ...
Reimer, Maria Hellström +8 more
core +1 more source
The Response Surface Methodology revisited – comparison of analytical and non-parametric approaches
Production Engineering Archives, 2018 Since G.E.P. Box introduced central composite designs in early fifties of 20th century, the classic design of experiments (DoE) utilizes response surface models (RSM), however usually limited to the simple form of low-degree polynomials.
Osocha Przemysław, Podgórski Jordan
doaj +1 more source