Results 81 to 90 of about 1,535,464 (268)
Optimal development of apoptotic cells-mimicking liposomes targeting macrophages
Journal of NanobiotechnologyMacrophages are multifunctional innate immune cells that play indispensable roles in homeostasis, tissue repair, and immune regulation. However, dysregulated activation of macrophages is implicated in the pathogenesis of various human disorders, making ...
Li Zhang +9 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
On the Potential of Function-Behavior-State (FBS) Methodology for the Integration of Modeling Tools [PDF]
, 2009 Organised by: Cranfield UniversityCurrent mechatronic products tend to be very complex systems. A design team is necessary to develop such products, and appropriate modeling and design support tools are essential to aid the design team.
Alvarez Cabrera, A. A. +2 more
core
PLM and early stages collaboration in interactive design, a case study in the glass industry [PDF]
, 2014 Product design activity is traditionally presented as a succession of four to six stages. In the early stages of design, during the search for concepts, multi-disciplinary teams are working together, sometimes on the fringe of the digital design chain ...
VERON, Philippe, SEGONDS, Frederic
core +1 more source
Designing an Autonomous Underwater Vehicle hull shape with direct approach
نشریه مهندسی دریا, 2018 Hydrodynamic design of the exterior hull shape is a main step of body shape design. The effective parameters in this process include the length of the nose and tail, the blunt sections of nose and tail as well as the profiles of the nose and the tail. In
Majid Alijani +2 more
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Exploring The Term “experiment” In Industrial Design
, 2015 Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2007Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2007Bu çalışmada, endüstriyel tasarımda ‘deney’ kavramı araştırılır ve tasarımda ...
Küçüksayraç, Elif
core
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Design and Optimization of Cooling Plate for Battery Module of an Electric Vehicle
Applied Sciences, 2019 With the development of electric vehicles, much attention has been paid to the thermal management of batteries. The liquid cooling has been increasingly used instead of other cooling methods, such as air cooling and phase change material cooling. In this
Ben Ye +2 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source