Results 71 to 80 of about 3,979,734 (303)

Status of the LHCb Experiment [PDF]

open access: yes, 2000
We present the status of the LHCb experiment which will make precision measurements of CP violation in $B$ meson decays. The motivation for the experiment and an overview of the detector design are given.
Muheim, Franz
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The outline of the expert system for the design of experiment

open access: yesProduction Engineering Archives, 2018
The design of experiment (DoE) is a methodology originated from early 1920s when Fisher’s papers created the analysis of variance and first known experimental designs: latin squares.
Dwornicka Renata, Pietraszek Jacek
doaj   +1 more source

Optimal Designs to Develop and Support an Experimental Strategy on Innovation of Thermoforming Production Process

open access: yesStatistica, 2017
The experimental strategy developed thanks to the DOE methodology enhance innovation capability in the field of thermoforming production processes for active packaging. It is composed of three phases: i) material characterization, ii) production in pilot
Fabrizio Ronchi   +6 more
doaj   +1 more source

A Study on Development of Three-Dimensional Chocolate Printer [PDF]

open access: yes한국정밀공학회지, 2017
In this study, we developed a 3D chocolate printer and studied the conditions needed for chocolate printing. Because chocolate is a mixture of cocoa mass, cocoa butter and sugar particles, its properties vary with temperature, and care is required in ...
Kyu Eon Kim, Keun Park, Chibum Lee
doaj   +1 more source

Budget Feasible Mechanisms for Experimental Design

open access: yes, 2013
In the classical experimental design setting, an experimenter E has access to a population of $n$ potential experiment subjects $i\in \{1,...,n\}$, each associated with a vector of features $x_i\in R^d$.
A. Archer   +8 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Response Surface Methodology revisited – comparison of analytical and non-parametric approaches

open access: yesProduction Engineering Archives, 2018
Since G.E.P. Box introduced central composite designs in early fifties of 20th century, the classic design of experiments (DoE) utilizes response surface models (RSM), however usually limited to the simple form of low-degree polynomials.
Osocha Przemysław, Podgórski Jordan
doaj   +1 more source

Preliminary design of the redundant software experiment [PDF]

open access: yes
The goal of the present experiment is to characterize the fault distributions of highly reliable software replicates, constructed using techniques and environments which are similar to those used in comtemporary industrial software facilities.
Campbell, Roy   +8 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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