Results 21 to 30 of about 17,265,464 (329)
Optimization design in single wagon-wheel fuel grain of hybrid rocket motor
FirePhysChem, 2021 The grain design of hybrid rocket motor is a design of proper fuel grain geometry and flow adjustment scheme based on the total impulse, thrust, chamber pressure, length and outer diameter of combustion chamber.
Wei Tianfang +5 more
doaj +1 more source
Numerical product design: Springback prediction, compensation and optimization [PDF]
, 2007 Numerical simulations are being deployed widely for product design. However, the accuracy of the numerical tools is not yet always sufficiently accurate and reliable.
Bonte, M.H.A. +3 more
core +13 more sources
Forward or Backward: Lessons Learned from Small Molecule Drugs Approved by FDA from 2012 to 2022
Molecules, 2023 At every juncture in history, the design and identification of new drugs pose significant challenges. To gain valuable insights for future drug development, we conducted a detailed analysis of New Molecular Entitiy (NME) approved by the Food and Drug ...
Mingxiao Gu +3 more
doaj +1 more source
Quantization Design for Distributed Optimization [PDF]
, 2015 We consider the problem of solving a distributed optimization problem using a distributed computing platform, where the communication in the network is limited: each node can only communicate with its neighbours and the channel has a limited data-rate. A
Jones, Colin N. +2 more
core +3 more sources
Advances in Metaheuristic Algorithms for Optimal Design of Structures, 2019 Gerhard Venter (gventer_vrand.conl) *Vanderpla(ds Research and Development, bit.1767 S 8th St'reef. Suite 100, Colorado Springs. CO 80906Jaroslaw Sobieszczanski-Sobieski (j.sobieski:_larc.nasa.gov) *A_4SA Lcmgley Research Ce,_terMS 240, Hampton, I:4 ...
Gerhard Venter +1 more
semanticscholar +1 more source
Evolutionary Synthesis of HVAC System Configurations: Algorithm Development. [PDF]
, 2008 This paper describes the development of an optimization procedure for the synthesis of novel heating, ventilating, and air-conditioning (HVAC) system configurations. Novel HVAC system designs can be synthesized using model-based optimization methods. The
Angelov, Plamen +4 more
core +3 more sources
Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope
Acta Pharmaceutica Sinica B, 2022 The proteolysis targeting chimeras (PROTACs) technology has been rapidly developed since its birth in 2001, attracting rapidly growing attention of scientific institutes and pharmaceutical companies.
Sinan Ma +10 more
doaj +1 more source
, 2020 The Dakota (Design Analysis Kit for Optimization and Terascale Applications) toolkit provides a flexible and extensible interface between simulation codes and iterative analysis methods.
Brian M. Adams +13 more
semanticscholar +1 more source
, 2020 The Dakota toolkit provides a flexible and extensible interface between simulation codes and iterative analysis methods. Dakota contains algorithms for optimization with gradient and nongradient-based methods; uncertainty quantification with sampling ...
B. Adams +17 more
semanticscholar +1 more source
Multi-objective topology design optimization combined with robust optimization
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2023 Topology optimization (TO), which is a design optimization technique that does not require design parameters, has been attracting attention. TO has a high degree of freedom and can obtain a novel design shape suitable for desired purposes.
Akito MARUO +4 more
doaj +1 more source