Results 41 to 50 of about 11,290,757 (236)

A Concise and Efficient Total Synthesis of α-Mangostin and β-Mangostin from

Natural Product Communications, 2013
The concise, efficient synthesis of α-mangostin is described in eight simple steps with 8.3% overall yield. Highlights include a practical approach to construct the isopentene groups and other diverse groups at C–2 and C–8 of the xanthene skeleton ...
Dandan Xu, Ying Nie, Xizhou Liang, Ling Ji, Songyuan Hu, Qidong You, Fan Wang, Hongchun Ye, Jinxin Wang   +8 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Recognition and Positioning of Strawberries Based on Improved YOLOv7 and RGB-D Sensing

Agriculture
To improve the speed and accuracy of the methods used for the recognition and positioning of strawberry plants, this paper is concerned with the detection of elevated-substrate strawberries and their picking points, using a strawberry picking robot ...
Yuwen Li, Wei Wang, Xiaohuan Guo, Xiaorong Wang, Yizhe Liu, Daren Wang   +5 more
doaj   +1 more source

BKM120 sensitizes BRCA-proficient triple negative breast cancer cells to olaparib through regulating FOXM1 and Exo1 expression

Scientific Reports, 2021
Poly (ADP-ribose) polymerase (PARP) inhibitors offer a significant clinical benefit for triple-negative breast cancers (TNBCs) with BRCA1/2 mutation. However, the narrow clinical indication limits the development of PARP inhibitors.
Yu Li, Yuantao Wang, Wanpeng Zhang, Xinchen Wang, Lu Chen, Shuping Wang   +5 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Design Optimization of a Multi-Megawatt Wind Turbine Blade with the NPU-MWA Airfoil Family

Energies, 2019
A new airfoil family, called NPU-MWA (Northwestern Polytechnical University Multi-megawatt Wind-turbine A-series) airfoils, was designed to improve both aerodynamic and structural performance, with the outboard airfoils being designed at high design lift
Jianhua Xu, Zhonghua Han, Xiaochao Yan, Wenping Song   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Advances in the structures, mechanisms and targeting of molecular chaperones

Signal Transduction and Targeted Therapy
Molecular chaperones, a class of complex client regulatory systems, play significant roles in the prevention of protein misfolding and abnormal aggregation, the modulation of protein homeostasis, and the protection of cells from damage under constantly ...
Jinying Gu, Yanyi He, Chenxi He, Qiuyue Zhang, Qifei Huang, Shangjun Bai, Ruoning Wang, Qidong You, Lei Wang   +8 more
doaj   +1 more source

Depth-Based Feature Recognition of Blind Pockets and Islands from STEP AP242 CAD Models for Milling Applications

Al-Khawarizmi Engineering Journal
The identification of blind pocket and island features in modern computer-aided design (CAD) and in the manufacturing of 3D CAD models is crucial. It ensures the accuracy and efficiency in the computer numerical control (CNC) machining process.
Amirulihsan Mohamad, Zammeri Abd Rahman, Saiful Bahri Mohamed, Muhammad Haziq Omar, Razwan Rohimi , Muhammad Abdulrahim Rabbani Md Sharizam, Tengku Mohd Sharir Tengku Sulaiman, Mohamad Minhat, Wawan Trisnadi Putra   +8 more
doaj   +1 more source