Results 41 to 50 of about 2,311,595 (304)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Recognition and Positioning of Fresh Tea Buds Using YOLOv4-lighted + ICBAM Model and RGB-D Sensing
Agriculture, 2023 To overcome the low recognition accuracy, slow speed, and difficulty in locating the picking points of tea buds, this paper is concerned with the development of a deep learning method, based on the You Only Look Once Version 4 (YOLOv4) object detection ...
Shudan Guo +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait +23 more
wiley +1 more source
MoleculesMolecular glue degraders (MGDs) constitute a class of innovative therapeutic agents within the field of targeted protein degradation (TPD). In contrast to proteolysis-targeting chimeras (PROTACs), MGDs induce protein degradation by stabilizing the ...
Yifan Zhang +7 more
doaj +1 more source
A Concise and Efficient Total Synthesis of α-Mangostin and β-Mangostin from
Natural Product Communications, 2013 The concise, efficient synthesis of α-mangostin is described in eight simple steps with 8.3% overall yield. Highlights include a practical approach to construct the isopentene groups and other diverse groups at C–2 and C–8 of the xanthene skeleton ...
Dandan Xu +8 more
doaj +1 more source
A Powerful Optimization Tool for Analog Integrated Circuits Design [PDF]
, 2013 This paper presents a new optimization tool for analog circuit design. Proposed tool is based on the robust version of the differential evolution optimization method. Corners of technology, temperature, voltage and current supplies are taken into account
Jakovenko, J., Kubar, M.
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Performance-based optimization of structures: theory and applications [PDF]
, 2005 Performance-based Optimization of Structures introduces a method to bridge the gap between optimization theory and its practical applications to structural engineering.
Liang, Qing Quan
core
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
Design Optimization of a Multi-Megawatt Wind Turbine Blade with the NPU-MWA Airfoil Family
Energies, 2019 A new airfoil family, called NPU-MWA (Northwestern Polytechnical University Multi-megawatt Wind-turbine A-series) airfoils, was designed to improve both aerodynamic and structural performance, with the outboard airfoils being designed at high design lift
Jianhua Xu +3 more
doaj +1 more source