Results 41 to 50 of about 903,165 (318)

A Concise and Efficient Total Synthesis of α-Mangostin and β-Mangostin from

open access: yesNatural Product Communications, 2013
The concise, efficient synthesis of α-mangostin is described in eight simple steps with 8.3% overall yield. Highlights include a practical approach to construct the isopentene groups and other diverse groups at C–2 and C–8 of the xanthene skeleton ...
Dandan Xu   +8 more
doaj   +1 more source

Recognition and Positioning of Fresh Tea Buds Using YOLOv4-lighted + ICBAM Model and RGB-D Sensing

open access: yesAgriculture, 2023
To overcome the low recognition accuracy, slow speed, and difficulty in locating the picking points of tea buds, this paper is concerned with the development of a deep learning method, based on the You Only Look Once Version 4 (YOLOv4) object detection ...
Shudan Guo   +7 more
doaj   +1 more source

Optimal Queue Design

open access: yesProceedings of the 22nd ACM Conference on Economics and Computation, 2020
We study the optimal method for rationing scarce resources through a queue system. The designer controls agents' entry into a queue and their exit, their service priority -- or queueing discipline -- as well as their information about queue priorities, while providing them with the incentive to join the queue and, importantly, to stay in the queue ...
Yeon-Koo Che, Olivier Tercieux
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Design Optimization of a Multi-Megawatt Wind Turbine Blade with the NPU-MWA Airfoil Family

open access: yesEnergies, 2019
A new airfoil family, called NPU-MWA (Northwestern Polytechnical University Multi-megawatt Wind-turbine A-series) airfoils, was designed to improve both aerodynamic and structural performance, with the outboard airfoils being designed at high design lift
Jianhua Xu   +3 more
doaj   +1 more source

A hydrogen peroxide responsive prodrug of Keap1-Nrf2 inhibitor for improving oral absorption and selective activation in inflammatory conditions

open access: yesRedox Biology, 2020
Transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2) and its negative regulator, the E3 ligase adaptor Kelch-like ECH-associated protein 1 (Keap1), control the redox and metabolic homeostasis and oxidative stress.
Mengchen Lu   +4 more
doaj   +1 more source

Optimal Experimental Designs

open access: yesThe Annals of Mathematical Statistics, 1966
Abstract : This paper presents a number of results concerning the theory of the optimal design of experiments initiated and principal developed by Elfving, Kiefer and Wolfowitz. The paper contains approximately half expository and half new material. The proofs are mostly new and presented in a unified manner.
Karlin, Samuel, Studden, William J.
openaire   +2 more sources

Optimal Platform Design

open access: yesCoRR, 2014
There is some overlap between this paper and the paper "Optimal Mechanism Design and Money Burning," which appeared in the STOC 2008 conference and as arXiv:0804.2097. However, the focus of this paper is different, with some of our earlier results omitted and several new results ...
Jason D. Hartline, Tim Roughgarden
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy